Accelerate Diagnostics, Inc.

Intelligent Medicine, Inc.

Other

Accelr8 Technology Corporation

Med General, Inc.

Izi Corporation

Accelrs Technology Corporation

Amidex, Inc.

Ivion Corporation

Isis Medical Instruments

David C Howson

Steven W Metzger

Daniel A Buttry

David A Goldberg

Steven Scott Saavedra

John A Popken

Steven F Bierman

Michael W Fellinger

Alena Shamsheyeva

Richard M Altobellis

Jens Axelgaard

Andrew Donovan Smith

Gary T Carroll

J Donald Pauley

Michael V Wiernicki

Eva S Zinreich

Simion J Zinreich

Kenneth Robert Hance

James E Heule

Frederick L Stone

Bennett J Scharf

Walter E Oshetski

Frederick Mark Paz

Richard A Simonelli

Mark G Scattergood

John A Perhay

Robert E Havranek

Systems and methods for rapid determination of microorganism growth and antimicrobial agent susceptibility and/or resistance are disclosed.

Rapid determination of microbial growth and antimicrobial susceptibility

The present invention relates to moving microorganisms to a surface, where they are grown in the presence and absence of antimicrobials, and by monitoring the growth of the microorganisms over time in the two conditions, their susceptibility to the antimicrobials can be determined. The microorganisms can be moved to the surface through electrophoresis, centrifugation or filtration. When the movement involves electrophoresis, the presence of oxidizing and reducing reagents lowers the voltage at which electrophoretic force can be generated and allows a broader range of means by which the target can be detected. Monitoring can comprise optical detection, and most conveniently includes the detection of individual microorganisms. The microorganisms can be stained in order to give information about their response to antimicrobials.

Sensitive and rapid determination of antimicrobial susceptibility

This disclosure is related to systems and methods for rapid determination of microorganism growth and antimicrobial agent susceptibility and/or resistance.

A method for the detection of microorganisms in a sample comprising contacting said sample with a biosensor concentration module, allowing microorganisms to grow for a first period of time and detecting growth of discrete microorganisms as an indication of the presence of said microorganisms.

Rapid microbial detection and antimicrobial susceptibility testing

Rapid microbial detection and antimicrobial susceptibiility testing

Aerosol collectorsinclude pre-collection filters, aerosol collection chambers, and other exhaled breath conditioning and control features for providing not only accurate and efficient, but also reliable and reproducible aerosol collections that can be used in standardizations and can be compared in meaningful ways to other exhaled breath aerosol collections from the same test subject and from different test subjects. The aerosol collectorexample includes electrostatic collection components, and the aerosol collectorincludes nucleating condensation componentsand vortex collection components. Both include analyte extraction apparatus

Breath aerosol management and collection system

The device of the present application, an adhesive disk, relates to non-invasive multi-modality radiographic surface markers and provides means for marking patients and diagnostic images taken of those patients through different methods including X-Ray, Computerized Tomography, Positron Emission Tomograph, and Nuclear Magnetic Resonance Imaging among others. The device of the present application also provides means for enabling the accurate location of internal structures of a patient.

Non-invasive multi-modality radiographic surface markers

A tubular adaptor releasably interconnects a conventional IV catheter hub to fluid supply tubing. A latching clip slidably mounted on the adaptor cooperates with flange portions on the catheter to secure the interconnection between the proximal end of the catheter and the adaptor. The adaptor is snapped into a base attached to the patient's skin by an adhesive pad. After the catheter connection is made, the adaptor, together with the clip, is rotated about 90.degree. on the base into a low profile position, wherein the clip is close to the patient's skin.

Catheterization system with universal retention device and method of use

A sideport connector for an IV catheterization system is disclosed in which a secure connection can be maintained with standard Y-shaped sideport connectors, such as a septum-type connector. The connector of the present invention comprises a clip having a collar which slidably and, optionally, rotatably engages the septum in order to prevent accidental disengagement. The clip is prevented from disengaging motion by, preferably, a ratchet-pawl mechanism. In another embodiment, the clip can be mounted on the branch of the Y-shaped sideport. The connector also comprises a needle shield or, optionally, a cap to prevent self-injection and contamination.

Sideport connector for catherization system

Safety enhanced device and method are disclosed for effecting application of a therapeutic agent. A removable and operationally non-volatile programmable element is used to control operation of a therapeutic agent delivery unit. A computer, operationally independent of the delivery unit, is utilized to establish coded information for programming of the programmable element while removed from the delivery unit. Operation of the delivery unit according to the program then established for the programmable element is simulated at the computer prior to actual programming of the programmable element to insure the integrity of subsequent delivery of the therapeutic agent to a patient by the delivery unit. The programmable element effects independent delivery of therapeutic agents in each of a plurality of channels under the control of the programmable element. The programmable element is programmed to establish a flow profile that is customized for a particular patient during each minute of each day, and patient demand for therapeutic agents can also be accommodated with safeguards being included to assure proper dispensing.

Safety enhanced device and method for effecting application of a

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Denver, CO, United States of America

David C Howson