Depuy Synthes Products, Inc.

Advanced Technologies and Regenerative Medicine, LLC

Cordis Corporation

Ethicon, Gmbh

David C Colter

Anna Gosiewska

Agnieszka Seyda

Christian C Kazanecki

Kevin L Cooper

Sridevi N Dhanaraj

Angelo G Scopelianos

Charito S Buensuceso

Anthony J Kihm

Brian C Kramer

Chunlin Yang

Darin J Messina

Iksoo Chun

Ian Ross Harris

Raymond S Shissias

Carrie H Fang

Christine K Ward

Heike Walles

Anke Hoppensack

Johanna Schanz

Thoppil Mathew John

Christian Kazanecki

Jan Hansmann

Anna C Gosiewska

Dhanaraj Sridevi

Compositions and methods of using cells derived from umbilical cord tissue to stimulate and support lung tissue angiogenesis, to improve blood flow to lung tissue, to regenerate, repair, and improve lung tissue damaged by lung disease, disorder and/or injury, and to protect lung tissue from damage caused by lung disease, disorder and/or injury in a patient.

Treatment of lung and pulmonary diseases and disorders

Isolated or purified mammalian kidney-derived cell populations from mammalian kidney tissue are provided. Methods are provided for the isolation and purification of the mammalian kidney-derived cell population. Methods for treating kidney disease are provided by administration of the isolated or purified mammalian kidney-derived cell population to a mammalian subject.

Kidney-derived cells and methods of use in tissue repair and regeneration

An isolated mammalian internal mammary artery-derived cell is disclosed. Furthermore, methods of isolating the mammalian internal mammary artery-derived cell are disclosed. The cell is useful in tissue engineering technologies, specifically in vascular tissue engineering.

Mammary artery derived cells and methods of use in tissue repair and regeneration

Provided are therapeutic implants comprising renal tissue encapsulated within a polymer bead. Also disclosed are methods for treating a disease state in a subject comprising implanting within said subject a therapeutic implant comprising renal tissue encapsulated within a polymer bead. Also provided are methods for making a therapeutic implant comprising: providing renal tissue; mixing the renal tissue with a solution comprising a polymer, thereby forming a tissue-polymer suspension; extruding the tissue-polymer suspension into an bead-forming solution, thereby forming a therapeutic implant comprising beads of said polymer within which the renal tissue is encapsulated.

Encapsulated kidney tissue

Compositions and methods of using tissue engineered blood vessels to repair and regenerate blood vessels of patients with vascular disease are disclosed.

Tissue engineered blood vessel

Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.

Postpartum cells derived from umbilical tissue and methods of making and using the same

Methods for treating a patient having a disease or damage to at least one kidney are provided. The methods comprise administering cells obtained from human umbilical cord tissue, or administering pharmaceutical compositions comprising such cells or prepared from such cells. When administered, the cells promote and support the repair and regeneration of the diseased or damaged kidney tissue in the patient. Pharmaceutical compositions for use in the inventive methods, as well as kits for practicing the methods are also provided.

Repair and regeneration of renal tissue using human umbilical cord tissue-derived cells

Growing community of inventors

Hamilton, NJ, United States of America

David C Colter