Aradigm Corporation

Genentech, Inc.

Oregon State University

Grifols, S.a.

Genetech, Inc.

David C Cipolla

James Blanchard

Igor Gonda

Luiz Eduardo Moreira Bermudez

Steven J Shire

Tue H Nguyen

Reid M Rubsamen

Jeffrey A Schuster

Stephen J Farr

Peter M Lloyd

Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.

Liposomal ciprofloxacin formulations with activity against non-tuberculous mycobacteria

A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.

Concentrated, inhalable ciprofloxacin formulation

Methods for formulating and compositions of immediate and sustained release liposomal products which comprise a surfactant that interacts with liposomes to effect drug release therefrom, and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.

Inhaled surfactant-modified liposomal formulations providing both an immediate and sustained release profile

Methods for formulating a liposome comprised of a surfactant and a cryopreservative that can be frozen for long term stability, and upon thawing provides an immediate and sustained release delivery profile. Specific liposome formulations include anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.

Liposomal formulations that form drug nanocrystals after freeze-thaw

Liposomal ciprofloxacin formulations with encapsulated ciprofloxacin nanocrystals

A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposomes which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions.

Concentrated, inhalable antibiotic formulation

Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.

Growing community of inventors

San Ramon, CA, United States of America

David C Cipolla