Purdue Research Foundation

David Brownholland

Philip Stewart Low

Cagri Abdullah Savran

David H Thompson

Chun-Li Chang

Ghanashyam S Acharya

Derek Doorneweerd

Walter A Henne

Systems and methods for rapid and ultrasensitive detection of target biomolecules in a sample are presented. The detection of biomolecules is achieved through a synergistic use of immunoseparation and diffractometry, and the formation of antibody-biomolecule-ligand sandwich complexes that form diffraction gratings. Characteristic diffraction patterns are then produced upon illumination of the diffraction gratings with light. The diffraction patterns can be used to detect very low amounts of biomolecules present in the sample.

Ultrasensitive detection of biomolecules using immunoseparation and diffractometry

Growing community of inventors

West Lafayette, IN, United States of America

David Brownholland