Wisconsin Alumni Research Foundation

David Belair

William Leo Murphy

Ngoc Nhi Le

Michael P Schwartz

Michael W Toepke

Stefan Zorn

Matthew Brian Parlato

William T Daly

Eric Huy Dang Nguyen

Connie Sue Chamberlain

Hamisha Ardalani

Matthew Zanotelli

Nicholas Impellitteri

Vascular endothelial growth factor VEGF-sequestering hydrogel microspheres that have been prepared to selectively bind VEGF from blood products are disclosed herein. In one particular embodiment, the microspheres bind VEGF as part of an intra-operative process such that the growth factor can be removed from the blood products before the products are used in a clinical procedure.

Hydrogel microspheres containing peptide ligands for growth factor regulation in blood products

Hydrogel Compositions and methods of using hydrogel compositions are disclosed. Advantageously, the hydrogel compositions offer the ability to rapidly screen substrate components for influencing cell attachment, spreading, proliferation, migration, and differentiation. In particularly suitable embodiments, the hydrogel compositions of the present disclosure may be used to promote tubulogenesis of endothelial cells.

Hydrogel compositions for use in promoting tubulogenesis

Growing community of inventors

Madison, WI, United States of America

David Belair