Friedrich Miescher Institute for Biomedical Research

Novartis Forschungsstiftung Zweigniederlassung Friedrich Miescher Institute for Biomedical Research

David Balya

Botond Roska

Pamela Lagali

Volker Busskamp

The present invention relates to the use of an isolated nucleic acid molecule comprising a nucleotide sequence coding for a hyperpolarizing light-gated ion channel or pump gene from an archeon or for a light-active fragment of said gene, or the nucleotide sequence complementary to said nucleotide sequence, for treating or ameliorating blindness. The light-gated ion channel or pump gene can be a halorhodopsin gene.

Therapeutical tools and methods for treating blindness

The present inventions relates to the use of an isolated nucleic acid molecule comprising a nucleotide sequence coding for a hyperpolarizing light-gated ion channel or pump gene from an archeon or for a light-active fragment of said gene, or the nucleotide sequence complementary to said nucleotide sequence, for treating or ameliorating blindness. The light-gated ion channel or pump gene can be a halorhodopsin gene.

Growing community of inventors

Basel, Switzerland

David Balya