Eastman-kodak Company

Ortho-clinical Diagnostics, Inc

David B LaTart

John C Mauck

Ignazio S Ponticello

Douglas Lincoln Vizard

Richard George Chubet

Robert Edwin Emmons

Dietmar Karl Freund

Paul James Heaney

Richard C Sutton

Hans W Osterhoudt

James R Schaeffer

Kenneth G Christy, Jr

Robert F Winterkorn

Thomas Arter

Wayne Weber

A dry analytical element is disclosed which can be used to sensitively and rapidly detect and quantitate protein. The assays are carried out using a dye that reacts with protein and molybdate ion to produce a measurable change in the spectral absorption of the dye. Also disclosed are polymers which stabilize and enhance the accuracy of the assay, and compounds which reduce interference by bicarbonate.

Dry analytical elements for the determination of protein

A dry, removable analytical element can be used to detect chemiluminescent signals produced from the reaction of peroxidase and a chemiluminescent detection system. The analytical element contains at least two layers, the outer layer being non-tacky and water-soluble or water-permeable, and used to contact a gel plate or transblotting membrane in which multiple analytes are located. The resulting signal can be recorded using a photosensitive element. Test kits include the various packaged components needed to use the analytical element for analyte detection. Within the element are critical amounts of oxidase and an oxidase substrate for highly sensitive analyte detection.

Dry elements, test devices, test kits and methods for chemiluminescent

Described are novel acrylic monomers, homopolymers and copolymers prepared therefrom, and electrophoresis gel media prepared by crosslinking certain copolymers of the invention by a crosslinking reaction that does not involve a free-radical vinyl addition mechanism.

Electrophoresis element comprising a polymer containing a haloacetamido

Preformed, water-soluble, acrylamide based copolymers comprising a minor proportion of a comonomer, which comonomer contains a site for a crosslinking reaction with a selected crosslinking agent by a reaction that does not involve a free-radical vinyl addition mechanism, which copolymers have M.sub.w and M.sub.n values within selected ranges, can be conveniently and safely used to prepare electrophoresis gel media in situ.

Polymeric electrophoresis media

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Rochester, NY, United States of America

David B LaTart