Sanofi-A Ventis Deutschland Gmbh

Sanofi

Becton Dickinson and Company Limited

Dca Design International Limited

Ceramaspeed Limited

Bio-Rad Laboratories, Inc.

Provalis Diagnostics Ltd

Francis Henry Lee

Bio-Rad Laboratories Deeside Ltd.

David Aubrey Plumptre

Robert F Veasey

Robert Perkins

Malcolm Stanley Boyd

Matthew Meredith Jones

Paul Richard Draper

Joseph Butler

Oliver Charles Gazeley

Christopher Clarkson Jones

Anthony Paul Morris

Paul Roger Griffin

Naceur Rekaya

James Alexander Senior

James J May

Garen Kouyoumjian

David Richard Mercer

Gareth James Lewis

Aidan Michael O'Hare

Catherine Anne MacDonald

Richard Letham

Richard James Vincent Avery

Samuel Steel

Craig Ashley Mason

Michael Schabbach

Simon Lewis Bilton

Steven Wimpenny

Christopher John Jones

Felix Kramer

Richard James Thomas

Hugh Smith

Samuel Ghazaros

Brian Charles Molyneux

Ronald Antony Smith

Daniel Edward Clark

Beat Wyss

Christopher James Smith

Daniel Thomas De Sausmarez Lintell

Stephen Francis Gilmore

William Marsh

Andrew Mark Lindsay

Neal Alexander Blundred

Frank Erbstein

Ian McFaul

Christopher Nigel Langley

James Alexander Davies

Philipp Müller

Michael Jugl

Michael Vincent Quinn

James Leslie Rhodri Jones

John David Cross

Michael Cameron Bainton

Maurice Toporek

David Martin Leak

Peter Ravenscroft Wilkins

Günther Sendatzki

Daniel David Higgins

David Alan Percival

Philipp Muller

Timothy Giles Claughton

Trivikrama Bhanoji Pala

Philip Song

Peter Quinn

Thomas Frederick Osman

Elliot Baxter

Warren Terry

Jamie Anthony Salter

Javier Eduardo Nadal

Harry Robert Lester

Prasannah Nanayakkara

Robert Frederick Veasey

David Sanders

Elliot L Ortiz

Robert Woolston

Aled Meredydd James

Christoph Dette

William Geoffrey Arthur Marsh

Christian Pommereau

Markus Ploch

Carmen Patricia Keating

Stephen John Minshull

Elizabeth Anne Marshall

Sophie Louise Sladen

Catherine Anne Macdonald

Patrick Gerard Linnane

Aidan Michael O'hare

Paul Jansen

Gavin Newman

Oliver Benjamin Brown

James Lewis Gareth

Thomas Khong

Jamie Salter

Roberts Frederick Veasey

Robert Frederick Veasy

James May

Malcom Boyd

Richard James Avery

Aidan Michael O'HARE

Christopher Jones

The present disclosure refers to a housing element for a drug delivery device. The housing element comprises longitudinal axis and defines an interior space for receiving components of a drive mechanism of the drug delivery device and at least a portion of a cartridge of the drug delivery device. The housing element comprises an engagement feature for axially constraining the housing element to a cartridge holder of the drug delivery device. In order to constrain the cartridge in the housing element, it further comprises at least one crush web protruding radially inwards into the interior space. The at least one crush web is angled relative to the longitudinal axis of the housing element by at least 3° such that when the cartridge is introduced into the interior space the at least one crush web folds radially outwards.

Housing element and drug delivery device herewith

A drug delivery device comprising a housing with an opening, a piston rod having a proximal end and a distal end, and a bearing. The piston rod is adapted to engage the opening for guiding the piston rod during a movement of the piston rod relative to the housing. The piston rod also includes a first attachment element located at the distal end. The bearing has a second attachment element for rotatable attachment of the bearing at the distal end of the piston rod. The first attachment element and/or the second attachment element is elastically deformable in a radial direction for snap engagement of the piston rod and the bearing. The opening is adapted to receive the first attachment element and the second attachment element if attached to each other but preventing disengagement of the first attachment element and the second attachment element if received in the opening.

Drug delivery device and assembly method for a drug delivery device

A cartridge assembly for a drug delivery device can include: a cartridge holder, a cartridge containing a drug, and a fixing member, wherein the cartridge holder includes an interior cartridge holding section, the cartridge being arranged in the cartridge holding section, wherein the fixing member is axially secured to the cartridge holder and secures the cartridge permanently in the cartridge holder.

Cartridge assembly for a drug delivery device and method for assembling the same

The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Medicament injection device

A system for a drug delivery device is provided. The system includes: a housing and a cartridge unit that is attachable to the housing or releasably attached to the housing. The cartridge unit includes a cartridge unit guide feature, the cartridge unit guide feature being provided to establish a guiding interface with the housing in order to guide relative movement of the cartridge unit and the housing with respect to one another when attaching the cartridge unit to the housing. The cartridge unit includes a cartridge unit interface feature, the cartridge unit interface feature being provided to form a further interface, in addition to the guiding interface, with the housing of the further interface being established when the cartridge unit is attached to the housing. The guiding interface is a bayonet-type interface which defines at least two different stages of movement between the cartridge unit and the housing when the cartridge unit is attached to the housing, a first stage with at least axial movement by a first stage axial distance in a first stage axial direction and a second stage with at least rotational movement by a second stage angle in a second stage rotational direction. The further interface is or includes a ramp interface.

System for a drug delivery device

Data collection devices for attachment to injection devices are disclosed. In one embodiment, the data collection device includes: a body attachable to a dial member of the injection device, a sensor arrangement comprising a sensor and a scale, and a processor. The sensor is configured to detect a rotation of the body relative to a trigger of the injection device. The processor is configured to detect a rotation of the body relative to the trigger. One of the sensor and the scale is arranged in or on the body and wherein the other one of the sensor and the scale is located on the trigger or is rotationally lockable to the trigger configured to detect a rotation of the body relative to the trigger.

Data collection device for attachment to an injection device

A cartridge assembly for a drug delivery device is described. The cartridge assembly includes a cartridge containing a drug, the cartridge including a dispensing end; a cartridge holder, the cartridge holder defining an interior cartridge holding section, where the cartridge is arranged within the cartridge holding section; and a fixing feature. The fixing feature includes a fixing surface, in particular a radially oriented surface, which is arranged to abut a cartridge surface of the cartridge, in particular a radially oriented surface, to prevent removal of the cartridge from the cartridge holder such that the cartridge is permanently secured in the cartridge holder.

Cartridge assembly for a drug delivery device and drug delivery device

A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.

Spacer assembly for drug delivery device

An assembly for a drug delivery device is provided, the assembly comprising a feedback feature. The feedback feature is configured to indicate an end of the dispense operation to a user by giving an audible and/or tactile feedback.

Assembly for a drug delivery device comprising a feedback feature

A cartridge assembly for a drug delivery device is described. The cartridge assembly includes (i) a cartridge containing a drug, the cartridge including a dispensing end; (ii) a cartridge holder, the cartridge holder defining an interior cartridge holding section, in which the cartridge is arranged within the cartridge holding section; and (iii) a fixing member. The fixing member includes a fixing surface arranged to abut a cartridge surface of the cartridge, in particular a radially oriented surface. The cartridge surface is a proximal surface which faces away from the dispensing end of the cartridge, and the cartridge surface is arranged between the dispensing end of the cartridge and the end opposite of the dispensing end. The fixing member includes a securing surface which is arranged to abut a holder surface of the cartridge holder. Further, a drug delivery device and a method for assembling the cartridge assembly are described.

Cartridge assembly and method for assembling the same

An arrangement of drug delivery devices is provided with interchangeable members and non-interchangeable members.

Drug delivery devices

The disclosure relates to an injection device for setting and injecting pre-set or user-selectable doses of a medicament, the injection device comprising an elongated housing defining a longitudinal direction and configured to accommodate a cartridge containing the medicament, and a detector arrangement operable to detect a relative movement between a first element and a second element. The first element is subject to a first movement relative to the second element along a first longitudinal direction for setting of a dose, the first element is subject to a second movement relative to the second element along a second longitudinal direction for dispensing of the dose, one of the first movement and the second movement is a helical movement, and the other one of the first movement and the second movement is a sliding movement in the longitudinal direction. The second element comprises at least one reference element fixed to the second element.

Injection device and detector arrangement

A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the mediacament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.

A drug delivery system for injecting a medicament includes a container including a closure and a stopper configured to move within the container from a pre-use position to a post-use position. The system includes a drive assembly configured to move the stopper between first and second positions, and a spacer assembly engaged with the stopper configured to be engaged by the drive assembly. The spacer assembly includes a first spacer portion received within the stopper, a second spacer portion spaced from the first spacer portion, an inner plunger, and a spacer shuttle received by the inner plunger. The inner plunger, the spacer shuttle, and the second portion are configured to move relative to the stopper, where movement of the second spacer portion is restricted by the spacer shuttle, movement of the spacer shuttle is restricted by the inner plunger, and movement of the inner plunger is restricted by the stopper.

Spacer assembly for drug delivery system

Growing community of inventors

Worcestershire, United Kingdom

David Aubrey Plumptre