Glaxo Group Limited

Convergence Pharmaceuticals Limited

David Amantini

Giuseppe Alvaro

Sandro Belvedere

Markus Bergauer

Roberto Profeta

Francesca Bonetti

Romano Di Fabio

Emiliano Castiglioni

Francesca Pavone

Compounds of formula (I), pharmaceutical compositions thereof, and methods for treatment using the same. 

Compounds

Disclosed are N-{[(1S,4S,6S)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-heteroarylamine derivatives having the following formula: wherein m, n, Het, R, Rand Rare as defined herein, and their use as orexin antagonists.

Heteroaryl derivatives of N-{[(1S,4S,6S)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-amine

This invention relates to imidazopyrazine substituted piperidine derivatives and their use as pharmaceuticals.

Imidazo[1,2-a]pyrazines as orexin receptor antagonists

This invention relates to imidazopyrimidine substituted piperidine derivatives and their use as pharmaceuticals.

Imidazo[1,2-A]pyrimidines as orexin receptor antagonists

The invention relates to quaternary &#x3b1;-aminocarboxyamide derivatives of formula (I), wherein R, R, R, R, R, R, X, q and n are as defined in claim, for treating diseases and conditions mediated by modulation of voltage-gated sodium channels. 

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Verona, Italy

David Amantini