University of Minnesota

Everest Medical Innovation Gmbh

David Alfonso Ramirez

Paul Anthony Iaizzo

John Bischof

Pegah Ranjbartehrani

Franz Schmidlin

Qi Shao

Andrew W Shaffer

Anthony Robert Prisco

Alexandre Porcello

Mikayle Ashlyn Holm

A surgical kit for providing a cryoprotective composition configured to be applied during cryotreatment of a patient includes: a first container containing a predetermined amount or volume of a biodegradable and/or bioerodible fluid agent; and a second container containing a predetermined amount or volume of a non-toxic cryoprotectant agent. The predetermined amount or volume of the of biodegradable and/or bioerodible fluid agent and the predetermined amount or volume of a non-toxic cryoprotectant agent are configured to be mixed together to form the cryoprotective composition in which a therapeutically effective amount of the cryoprotective composition deposited in a body space of the patient in proximity to the cryotreatment remains within at least a portion of the body space for a duration of the cryotreatment and at least a portion of a body tissue proximate to the body space is viable after the cryotreatment.

Cryoprotective compositions, surgical kits, and methods for protection of a surgical site during cryosurgery

A cryoprotective composition configured to be applied during cryotreatment of a patient includes at least one biodegradable and/or bioerodible fluid agent and at least one non-toxic cryoprotectant agent. A therapeutically effective amount of the cryoprotective composition deposited in a body space of the patient in proximity to the cryotreatment remains within at least a portion of the body space for a duration of the cryotreatment. At least a portion of a body tissue proximate to the body space is viable after the cryotreatment. A method of protecting a surgical site during prostate cryosurgery is also provided. The method includes injecting a therapeutically effective amount of the cryoprotective composition into the body space, wherein the body space is a periprostatic space of a patient.

Cryoprotective compositions and methods for protection of a surgical site during cryosurgery

A system and method for implanting heart assist devices. A model of a heart of a patient is formed based on images taken of the cardiothoracic cavity of the patient. A point is selected for insertion of the heart assist device based on the model. A graft location is selected on the aorta and a graft length for the graft is determined as a function of the implant location and the selected graft location.

System and method for implanting left ventricular assist devices

Growing community of inventors

Saint Paul, MN, United States of America

David Alfonso Ramirez