3m Innovative Properties Company

Diasorin S.p.a.

Focus Diagnostics, Inc.

David A Whitman

Peter D Ludowise

Michelle M Tabb

Maurice Exner

Kyle Armantrout

Lucien A E Jacky

Kevin D Landgrebe

Ranjani V Parthasarathy

Jeffrey D Smith

David M Read

Anthony E Bennett

Lucien AE Jacky

Kyle C Armantrout

Systems and methods for processing sample processing devices. The system can include a sample processing device comprising a detection chamber, a motor configured to rotate the sample processing device about an axis of rotation, and an optical module operatively positioned relative to the sample processing device and configured to determine whether a selected volume of material is present in the detection chamber of the sample processing device. The method can include rotating the sample processing device about an axis of rotation, and determining whether a selected volume of material is present in the detection chamber, while rotating the sample processing device. In some embodiments, determining whether a selected volume of material is present can be performed by optically interrogating the detection chamber for an optical property of the material.

Systems and methods for detecting the presence of a selected volume of material in a sample processing device

Chemical indicator compositions comprising a bismuth compound; elemental sulfur; and a compound with relatively high water solubility which makes the composition alkaline when exposed to water vapor at an elevated temperature; a chemical indicator comprising a substrate and the composition coated on at least a portion of a major surface of the substrate; and methods of making and using the chemical indicator are disclosed.

Chemical indicator compositions, indicators and methods

A system and method for volumetric metering on a sample processing device. The system can include a metering reservoir, and a waste reservoir positioned in fluid communication with a first end of the metering reservoir to catch excess liquid from the metering reservoir that exceeds a selected volume. The system can further include a capillary valve in fluid communication with the second end of the metering reservoir to inhibit liquid from exiting the metering reservoir until desired. The method can include metering the liquid by rotating the sample processing device to exert a first force on the liquid that is insufficient to move the liquid into the capillary valve, and rotating the sample processing device to exert a second force on the liquid that is greater than the first force to move the metered volume of the liquid to the process chamber via the capillary valve.

Systems and methods for volumetric metering on a sample processing device

Growing community of inventors

Saint Paul, MN, United States of America

David A Whitman