Ethicon, Gmbh

Cordis Corporation

Cardinal Health Switzerland 515 Gmbh

David A Szabo

Clifford A Dey

Robert J Cerwin

Konstantin K Ivanov

Mehmet Reyhan

William R Reinhardt

Robert Nunez

Donald Pompei

J Mark Findlay

Trevor John Beckett

Michael J Trezza, Ii

Valerie Anne Scott

David Gale

Greg R Furnish

Ben Morris

Paul A Johnson

Benjamin Wicks

Jonathan B Gabel

Robert A Daniele

Roddi J Simpson

Manfred Reiser

Manfred Hild

Matthew E Krever

Jervis P Lynch

Rolf Grotehusmann

Bernhard Frey

John M Findlay

Milton Cary Houston

Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravacularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.

Systems and methods for closing a vessel wound

Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from interventional procedures. The vessel wound closure system comprises at least a biocompatible, viscoelastic, self-sealing septum material injected onto the adventitia of the target vessel prior to performance of an interventional procedure. The prior injected septum material remains and seals the puncture wound of the target vessel even after various components associated with accessing the target vessel and the performance of the interventional procedure are removed from the target vessel and the puncture wound.

Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from interventional procedures. The vessel wound closure system generally comprises an introducer, and a hydratable hemostatic membrane dislodgable from over a portion of the introducer to seal a vessel wound upon hydration of the membrane. The membrane may include a glaze on an outside surface thereof to help control hydration of the membrane.

Vessel wound closure systems and method for sealing a puncture wound in a target vessel, such as those puncture wounds that occur from prior interventional procedures. A sealing member is deployed intravascularly into the target vessel, and an anchor member is deployed extravascularly of the target vessel. The sealing member and the anchor member are connected by a suture that may be drawn to tighten the sealing member and the anchor member relative to one another in order to effect the seal of the puncture wound. After tightening, the suture is secured to maintain the sealing member and the anchor member relative to one another in order to maintain the seal. Preferably, the anchor member, the suture and the sealing member are comprised of biocompatible, bioresorbable materials that are absorbed into the body after the sealing of the puncture wound has been achieved. The sealing member, suture and the anchor member are delivered by a delivery rod or other components over a guidewire or through an introducer already in place from the preceding interventional procedure.

A process for manufacturing a foil package from foil laminate sheet stock. The foil laminate has a top foil sheet and a bottom polymeric sheet laminated to the foil sheet. A cavity is molded into the bottom foil sheet, wherein the cavity has a bottom, a depth and a periphery, such that all of the periphery is substantially arcuate at any horizontal cross-section along the depth of the cavity. The top planar sheet is heat sealed to the bottom molded sheet. The molding process substantially reduces or eliminates curling.

Anti-curling foil manufacturing process

Automated packaging of surgical needle-suture assemblies includes a framing operation in which adjacent sheets of polymer coated aluminum foils are conveyed through a sequence of steps in an apparatus which produces frames containing plastic packets of needle-suture assemblies. A vision system having video cameras connected to a specially adapted computer enables monitoring the product traveling through the framing operation to detect various defects in the foil and in the product formation. Upon detection of a defect, the computer system can either identify and separate rejected product from good product or shut down the apparatus.

Method of and apparatus for detecting defects in a process for making

A process for applying a biobarrier member to a vent opening in a foil member used for medical device packaging. The process provides for cutting a biobarrier member from a roll of stock and sealing the biobarrier member about the vent opening in the foil member. The seal is tested for integrity and the biobarrier member is tested for porosity.

Process for microbial barrier vent to a foil package

A method of and apparatus for sealing unsealed surgical suture packages by applying heat and sealing pressure substantially simultaneously to both the sealed edge and the unsealed edge of an unsealed surgical suture package, thereby forming a sealed surgical suture package.

Method of and apparatus for sealing surgical suture packages

A package for maintaining a needle-suture product in a sterile condition includes a peelable foil container in which a peripheral heat seal defines a cavity for retaining a suture packet. The packet has a plastic tray and a stiff paper lid secured to the tray by hinged paper cleats extending into sockets in the tray. The lid covers most of the area of the tray, leaving an uncovered portion for accessing a needle mounted in the tray. A suture attached to the needle is coiled in a peripheral track in the tray so that an extended length of suture material can be retained in a relatively small space. The container has top and bottom aluminum foils with differentiated polymeric coatings on their interior surfaces, which are thermally fused to form the seal. Unsealed foil flaps are provided at one end of the container to enable peeling apart the foils to open the package.

Surgical suture package with peelable foil heat seal

Automated packaging of surgical needle-suture assemblies includes a framing operation in which adjacent sheets of polymer coated aluminum foils are conveyed through a sequence of steps in an apparatus which produces frames containing plastic packets of needle-suture assemblies. The apparatus pulls a web of foil off a large diameter feed roll and maintains web alignment as it travels down line through the apparatus by a system that optically detects transverse movement of the web as it is fed into the apparatus and adjusts the position of the feed roll relative to the centerline of travel using a hi-directional stepper motor. Discontinuities in the polymer coating on the top surface of the web of foil are automatically detected so that remedial steps can be taken to avoid processing defective sections of the web. A vision system having video cameras connected to a specially adapted computer enables monitoring the product travelling through the apparatus to detect various defects in the product formation. Upon detection of a defect, the computer system can either identify and separate rejected product from good product or shut down the apparatus. A servo drive system enables rapid and controllable advancement of the web down line in the apparatus.

Apparatus for feeding foil stock in a process for making sealed sterile

A method for making sterile suture packages employs a frame assembly line, a sterilization line and a blanker/cartoner line. A web of foil is advanced in a series of movements through the frame assembly line to assemble a frame containing needle-suture assemblies in a plurality of cavities in the frame, the frame having top and bottom aluminum foils with heat seal coatings on their facing surfaces. The cavities are formed in the bottom foil of each frame by a combination of pressurized air and mechanical plugs which are forced against the bottom foil and an underlying die having recesses for defining the cavities. A blanking operation following sterilization and sealing separates individual packages, each containing one needle-suture assembly, from the frame. The packages are then conveyed by belts through inspection stations and reoriented for loading into shipping cartons.

Growing community of inventors

Branchburg, NJ, United States of America

David A Szabo