Grifols Worldwide Operations Limited

Other

Ami Industries, Inc.

David A Ross

Thomas Barnett

Ralph Christian Crumrine

Douglas E Hoover

Mahesh Virupaxi Hosmani

Emik A Avakian

Akhil Rajagopal Kozhipuram

Pavan Kumar Krishna Kumar

Troy Brodish

Steven M Aperavich

Ralph Christian Crumine

Akhil Rajagopal Kozhipurami

Embodiments of the present invention provide methods for the treatment or prevention of infection-related immune conditions using compositions comprising IgM.

Method for the treatment or prevention of infection-related immune conditions using a composition comprising IgM

The present invention relates to methods of treatment of Hypoxia Inducible Factor (HIF)-related conditions, and in particular to methods of treatment of HIF-related conditions comprising the administration of a composition comprising transferrins.

Method of treatment of hypoxia inducible factor (HIF)-related conditions

Disclosed is an armrest assembly for a vehicle seat such as a pilot seat positioned in an aircraft cockpit. The armrest assembly generally includes a pivoting armrest and an arm pad repositionable relative to the armrest to change the arm pad width. The arm pad includes two functional sides each having a different width dimension. The arm pad is coupled to the armrest such that sequential translational and rotational motion of the arm pad moves one of the first and second sides into a use position atop the armrest and the other of the first and second sides into an out of use position alongside the armrest. The armrest assembly according to the present disclosure is ideal for use in tight quarters within the flight deck, among other installation environments requiring a functional armrest.

Vehicle seat armrest assembly with repositionable arm pad

Compositions and methods of the present invention prevent, inhibit or reduce the toxic effects of proteins and toxins secreted from microbes. A method for neutralizing microbial protein products in a subject comprises administering a composition to the subject, said composition comprising plasma-derived IgM and optionally one or more excipients in a pharmaceutical carrier, wherein the composition is administered in an amount effective to neutralize the microbial protein products.

Method for treating infectious diseases using a composition comprising plasma-derived immunoglobulin M (IgM)

A seat adjustment mechanism for an adjustable seat assembly includes an arcuate tilt column; a lift column; a first tilt slider block detachably engaged to the lift column and slideably engaged to the tilt column for moving the lift column between a plurality of tilt positions; and a first lift slider block slideably engaged to the lift column for moving between a plurality of lift positions independent of the plurality of tilt positions. The slider blocks, the lift columns, the tilt columns and the cross brace may be made of dissimilar materials and/or are easily replaced with alternative components.

Adjustable seat assembly

Method of treatment of Hypoxia Inducible Factor (HIF)-related conditions

This motor/generator produces rotational torque and/or electrical energy employing a flexible magnetically permeable circular band as a rotor that in operation is in physical contact with the stator, arching and curving forward in response to advancing magnetic fields along the stator surface. The stator may be comprised of either a typical three-phase winding, or a series of magnetic actuators arranged in a toroid for which the rotor band acts as a continuous armature. The rotor rotates as follows: an actuator to the left or right of an active actuator is activated to pull a rotor arch down to the stator surface; as this occurs, the previously active actuator is turned off and that part of the rotor springs away; the rotor moves clockwise or counterclockwise as the arches of the rotor are advanced forward or backward, respectively. Differential rotor movement provides speed reduction and torque enhancement without gears.

Flexible rotor sequentially actuated motor/generator

An inflatable, implantable prosthesis includes a flexible, inflatable, thin wall container of physiologically acceptable material provided with a self-sealing valve assembly which permits fluid to be introduced into or removed from said container to inflate or deflate the prosthesis. The self-sealing valve assembly includes a top having an outer wall and an inner wall which are sealed about their periphery to form an envelope which is filled with a self-sealing gel. The outer wall of the top is secured to the inside of the container and a side wall depends from the top and is connected to a bottom to define a chamber. The chamber has at least one opening in the bottom or side wall so that inflating fluid can pass to and from said chamber into the interior of the container. When inflating or deflating the container, the valve is opened by passing a needle through the envelope and self-sealing gel into the chamber; fluid is removed from or added to the container through the needle or a replacement catheter via the chamber. The chamber shields and protects the thin wall of the container from potentially damaging contact with the needle. The side walls of the chamber are comprised of a flexible material which permits the chamber to collapse to form a more compact uninflated container that may be implanted using a minimum size incision and which expands after implantation.

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Cary, NC, United States of America

David A Ross