Neuropace, Inc.

Other

David A Greene

Stephen T Archer

Patrick Gerard Mulligan

Patrick G Mulligan, Iv

Steve T Archer

Alfonso Chavez

Sharanya Arcot Desai

Emily A Mirro

Jacob A Mandell

A lead fixation device for securing a first portion of a lead relative to a hole formed through a skull includes a skull attachment member having an upper surface and a lower surface and a bore extending through and between the upper surface and the lower surface. The lead fixation device also includes a lead compression mechanism integral with the skull attachment member and aligned with the bore of the skull attachment member. The lead compression mechanism defines a passageway through the lead fixation device, which passageway is characterized by a diameter that is defined by the lead compression mechanism. The lead compression mechanism is configured to transition the diameter from a first size to a second size greater than the first size upon insertion of an implant tool through the passageway, and from the second size to the first size upon removal of the implant tool from the passageway.

Lead fixation devices for securing a lead to a cranium

An implanted neurostimulation system is configured to sense episodes of electrographic events and determine durations of episodes. Durations of electrographic events sensed by the implanted neurostimulation system are mapped with seizure probability biomarkers derived from records of the electrographic events to create a mapping function. A seizure probability biomarker that has a value desired for the operation of the implanted neurostimulation system is selected. The duration mapped to the selected seizure probability biomarker is identified and programmed into a control module of the implanted neurostimulation system as a programmed parameter that triggers the operation by the implanted neurostimulation system. The process may be repeated for other operations of the implanted neurostimulation system.

Systems and methods for controlling operation of an implanted neurostimulation system based on a mapping of episode durations and seizure probability biomarkers

An external data retrieval apparatus receives a low resolution version of a physiological signal from an active implantable medical device and determines if the physiological signal represents a clinically significant event. The apparatus provides an indication of such determination to the implantable medical device. If the physiological signal does represent a clinically significant event, the apparatus receives a full download of the physiological signal from the implantable device.

Use of a progressive compression encoding of physiologic waveform data in an implantable device to support discontinuing transmission of low-value data

A lead fixation accessory configured to be positioned over a skull hole and to transition between an opened state and a closed state during a lead implant procedure protects against lead migration by providing a mechanism for securing the lead in place at the skull hole while a stylet is removed from the lead. The lead fixation accessory remains in place after the implant procedure to provide chronic lead stability. A lead stabilization tool configured to access and grip a lead through a slotted cannula during the lead implant procedure also protects against lead migration by providing a mechanism for securing the lead in place at a point where the lead exits the skull hole while the slotted cannula is removed from the skull hole and peeled away from the lead.

Lead fixation accessory, lead stabilization tool, and related procedures

A rotating platform has a peripheral wall to form a catch basin. A donut shaped wrapper housing can hold perhaps 50-100 cigarette wrappers facing inbound with a closed end projecting out an outer wall exit hole into the catch basin. Tobacco or any work material is dropped onto the center of the rotating platform which may be motor driven. Centripetal forces urge the work material into the wrappers. Empty wrapper channel feed the excess material into the catch basin. A lid prevents loss of work material.

Centripetally assisted pre-formed cigarette wrapper filler

A lead fixation device for securing a medical lead in a human patient includes: a single-piece structure comprising: a top surface; a bottom surface; an outer perimeter; and an inner perimeter, the inner perimeter comprising: a diameter approximately equal to or smaller than a diameter of a burr hole into which the lead fixation device is designed to be deployed; a central bore extending longitudinally from the top surface through to the bottom surface, a portion of the central bore being located in approximately a center of the lead fixation device and comprising a central bore diameter; and at least one retention tract formed in the top surface of a cap of the lead fixation device, the retention tract configured for retaining, with an interference fit, a portion of a body of the medical lead in the lead fixation device.

Lead fixation device for securing a medical lead in a human patient

A rotating platform has a peripheral wall to form a catch basin. A donut shaped wrapper housing can hold perhaps 50-100 cigarette wrappers facing inbound with a closed end projecting out an outer wall exit hole into the catch basin. Tobacco or any work material is dropped onto the center of the rotating platform which may be motor driven. Centripetal forces urge the work material into the wrappers. Empty wrapper channels feed the excess material into the catch basin. A lid prevents loss of work material.

An external data retrieval apparatus includes a transceiver, and a processing system coupled to the transceiver. The processing system obtains a plurality of measures over a period of time. The measures relate to a quality of a communications channel between the data retrieval apparatus and an active implantable medical device. The processing system determines a trend in the plurality of measures over the period of time, and then determines a preferred time during which to retrieve data based on the trend.

Optimizing data retrieval from an active implantable medical device

An implantable seizure monitor can include at least one sensing electrode and an electronics module configured to detect, record and/or log neurological events. For example, the electronics module can be configured to detect brainwaves indicative of seizures, such as, for example, epileptic seizures, and to create a log indicating when such seizures occur. The implantable seizure monitor can include a cushioning member made of a soft material and configured to be implantable between the epidermis and cranium of a patient.

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Fort Wayne, IN, United States of America

David A Greene