Abbvie Inc.

Abbott Laboratories Corporation

Abbvie Bahamas Limited

David A DeGoey

Allan C Krueger

John T Randolph

Pamela L Donner

Warren M Kati

Rolf Wagner

Charles A Flentge

John K Pratt

Dachun Liu

Todd Warren Rockway

David A Betebenner

Clarence J Maring

Douglas K Hutchinson

Christopher E Motter

Tammie K Jinkerson

Mark A Matulenko

Charles W Hutchins

Michael D Tufano

Sachin V Patel

Yi Gao

Ryan G Keddy

Lissa T Nelson

Dale J Kempf

David J Grampovnik

Kevin R Woller

Kenton L Longenecker

Kathy A Sarris

Seble H Wagaw

Wenke Li

Mary E Bellizzi

Daniel D Caspi

Larry L Klein

William J Flosi

William A Carroll

Hui-Ju J Chen

Jean C Califano

Kent D Stewart

Ming Clinton Yeung

Marc J Scanio

Darold L Madigan

Geoff G Z Zhang

Arturo Perez-Medrano

Tongmei Li

Peggy Huang

Xiaochun Lou

Yaya Liu

Todd N Soltwedel

Marlon D Cowart

Chen Zhao

Anthony Ralph Haight

Jennifer M Frost

Rodger F Henry

John R Koenig

Jerome F Daanen

David M Barnes

Tami J Pilot-Matias

Sridhar Peddi

Xiu Chun Wang

Lei Shi

Shuang Chen

Meena V Patel

Michael E Kort

Yi-Yin Ku

William H Bunnelle

Bo Liu

Keith F McDaniel

Minghua Sun

Derek W Nelson

Rong Zhang

Brian S Brown

Andrew Bogdan

Eric A Voight

Curt S Cooper

Jason P Shanley

Brian E Green

David D Anderson

Brian D Wakefield

Liangjun Lu

Hillary M Peltier

Jean-Christophe C Califano

Robert J Carrick

John Hartung

Hongmei Mo

Wenping He

Preethi Krishnan

Christopher C Marvin

Nobuhiko Iwasaki

Vikram Kalthod

Akhteruzzaman Molla

Sherie V L Masse

Geoff T Halvorsen

Jaclyn Chau

Jyoti R Patel

Howard Robin Heyman

Augustine Osuma

Xiangdong Xu

Anurupa Shrestha

Brian J Kotecki

John E Hengeveld

Su Yu

The present invention features compounds effective in inhibiting active against Hepatitis C virus ('HCV') polymerase. The invention also features processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

Anti-viral compounds

Compounds effective in inhibiting replication of Hepatitis C virus ('HCV') are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein R, R, and Rare as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Na1.7 and/or Na1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.

6-heteroaryloxy- or 6-aryloxy-quinoline-2-carboxamides and method of use

Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein A, Rand Rare as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Na1.7 and/or Na1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.

Indazole ureas and method of use

Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein G, L, Zand Zare as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Na1.7 and/or Na1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.

(Indazol-4-yl) hexahydropyrrolopyrrolones and methods of use

This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.

Antiviral compounds and uses thereof

Anti-infective agents and uses thereof

Growing community of inventors

Salem, WI, United States of America

David A DeGoey