Medtronic, Inc.

Covidien LP

Other

Medtronics, Inc.

David A Anderson

Can Cinbis

Jonathan L Kuhn

James Kevin Carney

Mark T Marshall

Amy E Thompson-Nauman

John D Wahlstrand

Vladimir Pavlovich Nikolski

Robert T Sawchuk

Gregory A Younker

Richard J O'Brien

Avram Scheiner

Yong Kyun Cho

Saul E Greenhut

William John Havel

Aleksandre T Sambelashvili

Todd Jon Sheldon

Xusheng Zhang

Wade M Demmer

Karen J Kleckner

Jonathon E Giftakis

Rodolphe Katra

Eric J Panken

D Curtis Deno

Randal C Schulhauser

Thomas J Mullen

James F Kelley

Steven Lawrence Waldhauser

John Wainwright

Naim S Istephanous

David R Bloem

Paul G Krause

Ekaterina M Ippolito

David M Steinhaus

Narendra K Simha

Jeffrey M Gillberg

Andrew J Ries

Eduardo N Warman

Matthew David Bonner

Shantanu Sarkar

Vinod Sharma

Mark R Boone

Todd M Zielinski

Hyun J Yoon

Brian Bruce Lee

Michael B Terry

Vincent P Ganion

Tom Dean Bennett

Zhendong Song

Xiaonan Shen

Nathalie Virag

Jason C Lee

Eric M Christensen

Jon E Thissen

Noah D Barka

Michael Andrew Reinert

Ashley L Galarneau

Erin D Grassl

Jeffrey M Huston

Lewis J Werner

James H Borowick

Scott DeFoe

Philip E Tracton

Robert T Sawchuck

In some examples, a device includes at least three electrodes a first pair of electrodes and a second pair of electrodes. The device also includes circuitry configured to generate a first cardiac signal based on a first differential signal received across the first pair, generate a first brain signal based on the first differential signal received across the first pair, generate a second cardiac signal based on a second differential signal received across the second pair, and generate a second brain signal based on the second differential signal received across the second pair. The circuitry is also configured to output a composite cardiac signal based on the first cardiac signal and the second cardiac signal and to output a composite brain signal based on the first brain signal and the second brain signal.

Determining composite signals from at least three electrodes

An implantable medical device has a therapy module configured to generate a composite pacing pulse including a series of at least two individual pulses. The therapy module is configured to generate the composite pacing pulse by generating a first pulse of the at least two individual pulses by selectively coupling a first portion of a plurality of capacitors to an output signal line and generate a second pulse of the at least two individual pulses by selectively coupling a second portion of the plurality of capacitors to the output signal line.

Extra-cardiovascular cardiac pacing system for delivering composite pacing pulses

A system comprises a sensor device and processing circuitry. The sensor device comprises a housing configured to be disposed above shoulders of a patient, a plurality of electrodes on the housing, a motion sensor, and sensing circuitry configured to sense a brain electrical signal and a cardiac electrical signal via the electrodes, and a motion signal via the motion sensor. The processing circuitry is configured to determine values over time of one or more parameters from the brain electrical signal, determine values over time of one or more parameters from the cardiac electrical signal, and generate at least one of a detection, prediction, or a classification a condition of the patient based on the values and the motion signal.

Detection of patient conditions using signals sensed on or near the head

This disclosure is directed to techniques for detecting and mitigating inaccurate sensing in a medical system. In some examples, one or more sensors of the medical system may include at least one electrode configured to sense an impedance of a portion of a patient's body proximate to the electrode and processing circuitry of the medical system may detect an inaccuracy in the data corresponding to the one or more patient physiological parameters based upon data including at least the sensed impedance of the portion of the patient body; correct at least a portion of the inaccuracy in the data corresponding to the one or more patient physiological parameters; and generate, for display on a display device, output data indicating the inaccuracy in the data corresponding to the one or more patient physiological parameters.

Detection and mitigation of inaccurate sensing by an implanted sensor of a medical system

An extra-cardiovascular implantable cardioverter defibrillator (ICD) having a low voltage therapy module and a high voltage therapy module is configured to select, by a control module of the ICD, a pacing output configuration from at least a low-voltage pacing output configuration of the low voltage therapy module and a high-voltage pacing output configuration of the high voltage therapy module. The high voltage therapy module includes a high voltage capacitor having a first capacitance and the low voltage therapy module includes a plurality of low voltage capacitors each having up to a second capacitance that is less than the first capacitance. The ICD control module controls a respective one of the low voltage therapy module or the high voltage therapy module to deliver extra-cardiovascular pacing pulses in the selected pacing output configuration via extra-cardiovascular electrodes coupled to the ICD.

Extra-cardiovascular pacing by an implantable cardioverter defibrillator

The disclosure describes systems and techniques for detection of pump thrombosis in mechanical circulatory support (MCS) devices. An example pump thrombosis detection system includes a transducer and processing circuitry. The transducer may be configured to generate a signal representative of a mechanical wave from a mechanical circulatory support device. The processing circuitry is communicatively coupled to the transducer. The processing circuitry may be configured to determine an indication of pump thrombosis based on the signal and, based on the indication of pump thrombosis, control the pump thrombosis detection system to at least one of generate an alert or initiate an intervention.

Detection of pump thrombosis

An implantable medical device is configured to control a therapy module to couple a capacitor array comprising a plurality of capacitors to a plurality of extra-cardiovascular electrodes and control the therapy module to deliver a composite pacing pulse to a patient's heart via the plurality of extra-cardiovascular electrodes by sequentially discharging at least a portion of the plurality capacitors to produce a series of at least two individual pulses that define the composite pacing pulse.

An example pump thrombosis detection system includes a transducer and processing circuitry. The transducer may be configured to generate a signal representative of a mechanical wave from a mechanical circulatory support device. The processing circuitry is communicatively coupled to the transducer. The processing circuitry may be configured to determine an indication of pump thrombosis based on the signal and, based on the indication of pump thrombosis, control the pump thrombosis detection system to at least one of generate an alert or initiate an intervention.

An extra-cardiovascular implantable cardioverter defibrillator (ICD) is configured to induce a tachyarrhythmia by charging a high voltage capacitor to a voltage amplitude and delivering a series of pulses to a patient's heart by discharging the capacitor via an extra-cardiovascular electrode vector. Delivering the series of pulses includes recharging the high-voltage capacitor during an inter-pulse interval between consecutive pulses of the series of pulses.

Tachyarrhythmia induction by an extra-cardiovascular implantable cardioverter defibrillator

The exemplary systems and methods may monitor one or more signals to be used to assess the hemodynamic status of a patient. The one or more signals may be used to calculate, or determine, a plurality of pulse transit times. The plurality of pulse transit times may be used to determine hemodynamic status values that may be indicative of a patient's aggregate hemodynamic status.

Systems and methods for monitoring hemodynamic status

A medical device for monitoring delivery of a therapy that includes a therapy delivery module to deliver a therapy, a controller to set a therapy delivery control parameter, an optical sensor to produce a signal corresponding to tissue light attenuation, and a processor configured to compute a tissue oxygenation measurement from the optical sensor signal, wherein the controller, the optical sensor, and the processor operate cooperatively to determine a setting of the therapy delivery control parameter corresponding to a maximum tissue oxygenation.

Tissue oxygenation monitoring in heart failure

Growing community of inventors

Stanchfield, MN, United States of America

David A Anderson