Other

Medline Industries, Inc.

Eton Pharmaceuticals, Inc.

Advanced Respiratory Technologies, Inc.

Rubin, Darren

Darren Rubin

Howard A Rubin

The present invention provides pharmaceutical formulations of levorotatory-epinephrine, l-epinephrine, more potent and less toxic than existing pharmaceutical formulations of epinephrine, along with methods of producing and using these pharmaceutical formulations of l-epinephrine, including preventing and or treating hypotension and hemostasis under surgical anesthesia.

More potent and less toxic formulations of epinephrine and methods of medical use

The present disclosure describes a flavor element configured for providing flavor to a user of an electronic vaporizer, along with nicotine reduction methods. The flavor element includes a flavor material configured to provide the flavor and is configured to attach to the electronic vaporizer. When attached to the electronic vaporizer and during inhalation by the user using the electronic vaporizer, the flavor element is configured to provide the flavor to the user in parallel with an inhalable aerosol provided by the electronic vaporizer. The inhalable aerosol is provided by the electronic vaporizer by at least partially vaporizing a vaporizable substance via a vapor element. The flavor provided via the flavor material is separate from the vaporizable substance.

Flavor elements and methods of providing nonvaporized flavor to electronic vaporizers and E-cigarettes

Flavor elements and methods of providing nonvaporized flavor to electronic vaporizers and e-cigarettes

A first source of medical gas has a generally cylindrical male outlet with a cylindrical bore and a threaded outer cylindrical surface. A flexible cylindrical elastomeric medical gas tubing has an input end with a bushing making a flush abutment with the male outlet at the output orifice. An output end attaches to any of a plurality of medical gas utilizing devices, but preferably with a dampening disperser held in position in the space in the vicinity of a patient's nose and mouth. An annular flange of the input end bushing resides within a central cylindrical bored out region extending through the first end and nearly to the second end of a rotatable connector forming an interior surface of a connector with threads coupling with the threads of the male outlet. The second end is an annular abutment against the annular flange holding the input end tubing bushing against the outlet source and providing an airtight coupling. A gripping means is on the exterior surface of the connector.

Universal medical gas delivery system

The present invention provides pharmaceutical formulations of levorotatory-epinephrine, 1-epinephrine, more potent and less toxic than existing pharmaceutical formulations of epinephrine, along with methods of producing and using these pharmaceutical formulations of 1-epinephrine, including preventing and or treating hypotension and hemostasis under surgical anesthesia.

An example aerosol delivery device includes a mouthpiece having an airflow outlet, and an airflow passage extending between an airflow inlet and the airflow outlet. The example aerosol delivery device further includes a housing configured to receive a cartridge that includes an aerosolizable substance and a vapor element configured to heat the aerosolizable substance, and an internal power source configured to provide electrical power. The example aerosol delivery device further includes a controller coupled to the internal power source to receive a portion of the electrical power and configured to, when the cartridge is installed at the housing, cause the vapor element of the cartridge to heat the aerosolizable substance to release an aerosol into the airflow passage during an inhalation through the airflow outlet, and a connector configured to receive power from an external source to recharge the internal power source.

Systems and methods of aerosol delivery with airflow regulation

The present invention relates to longitudinally sectioned bullets and methods that pertain to a penetrable projectile structured to be discharged from a firearm and comprising at least two separable and penetrable, non-fused individual longitudinal body sections and at least one exterior binding element, including at the frontal region of said penetrable projectile, that holds the at least two non-fused individual longitudinal body sections together until they rupture inside of a target, thereby causing the penetrable individual longitudinal body sections to separate away from each other inside of the target as the projectile penetrates the target. The penetrable projectile is thus capable of controlled fragmentation against a soft target, and is optionally adapted to deliver at least one supplemental payload to a target to further damage said target.

Longitudinally sectioned firearms projectiles

A bullet projectile, not limited to a hollow point bullet, is made into a biological active bullet before loading and firing from a firearm with a method of incorporating an at least one biological active payload into an at least one externally facing cavity or channel of the bullet projectile to enhance the damage and lethality of the bullet projectile to produce at least one of embolism, infarct, necrosis, hemorrhage, enhanced loss of perfusion, anticoagulation, or a combination thereof in a target.

Biological active bullets, systems, and methods

The present invention provides improved pharmaceutical formulations for the treatment ofinfection and duodenal ulcer disease, and includes methods of preparation and methods of medicinal use of at least one proton pump inhibitor and at least two different antibiotics within the same solid oral dosage form, whereby at least one antibiotic is coated or encapsulated independently from at least one other antibiotic within this solid oral dosage form.

[object Object]

A hemostatic bullet projectile is for discharge from a firearm and for use as a weapon. The ammunition is a bullet in a cartridge. The bullet projectile includes, and is distinguished by, the use of at least one potentially biological active substance delivered to a bullet wound of a target and serving as a hemostatic agent to promote blood clotting and/or control hemorrhage in the bullet would to stabilize the target until surgery can be performed. Methods are included to promote blood clotting and/or control hemorrhage in at least one bullet wound by delivery of a hemostatic agent by the bullet projectile causing the wound as well as minimizing the risk of embolism from the hemostatic bullet projectile.

The present invention relates to longitudinally sectioned bullets and methods that pertain to a projectile structured to be discharged from a firearm and comprising at least two separable longitudinal body sections and at least one binding element that holds the at least two longitudinal body sections together, such as before impact with a target. Said projectile is thus capable of controlled fragmentation against a soft target. Said projectile is adapted to also contain at least one supplemental payload deliverable to a target to further damage said target.

Novel nebulizers and methods are provided for a nebulizer including a dialable negative pressure threshold valve that actuates in response to different negative pressures corresponding to different negative pressure threshold settings of actuation of the valve to influence inhalation effort, aerosol entrainment, and aerosol delivery.

Nebulizer having different negative pressure threshold settings

Pharmaceutical formulations for the treatment ofinfection and duodenal ulcer disease and methods of preparation and medicinal use of at least one proton pump inhibitor and at least two different antibiotics within the same solid oral dosage form, whereby at least one antibiotic is encapsulated independently from at least one other antibiotic within this solid oral dosage form.

A biological active bullet able to be discharged from a firearm, the ammunition essentially comprising a bullet in a cartridge, the bullet including, and distinguished by the use of, at least one potentially reactive chemical substance delivered to a target and undergoing at least one violent exothermic chemical reaction with a bodily fluid of said target, and having at least one biological effect in the target upon impact and penetration, while causing tissue damage in addition to the bullet wound, and thus, having additional functions and applications than prior art bullets, along with methods of use, that ensure enhanced damage and lethality.

The present invention relates to longitudinally sectioned bullets and more particularly pertains to a projectile structured to be discharged from a firearm and comprising at least two separable longitudinal body sections and at least one binding element that holds the at least two longitudinal body sections together, such as before impact with a target. Said projectile is thus capable of controlled fragmentation against a soft target. Said projectile is adapted to also contain at least one supplemental payload deliverable to a target.

Growing community of inventors

Largo, FL, United States of America

Darren Rubin