University of Akron

Other

University of Nebraska

Darrell H Reneker

Daniel J Smith

George G Chase

Tao Han

Woraphon Kataphinan

Alexander L Yarin

Hongfei Jia

Ping Wang

Dale Ertley

Songtao Wu

Matthew L Becker

Iksoo Chun

Mukerrem Cakmak

Charlene M Mello

Baris Yalcin

Michael S Sennett

Albert T McManus

Yaohua Gao

Heidi Schreuder-Gibson

Prathyusha Katta

Steven David Hudson

R K Eby

Camden Ertley

Joseph W Reneker

Jakapon Sunthornvarabhas

Oludotun Dosunmu

Guangyu Zhu

Srihari Rangarajan

Ketan Mehta

Wenxia Liu

Ravindrabharathi Narayanan

Sally Dabney

Sureeporn Tripatanasuwan

Yuris A Dzenis

Shahrzad Zarkoob

Daniel Smith

The present invention is generally directed to a liquid entrapping device having the capacity to absorb liquids. More particularly, the present invention is directed to a liquid entrapping device comprising an absorbent component, hydrophilic elastomeric fibrous component in fluid communication therewith, and optionally an adhesive component. The present invention is also directed to a liquid entrapping device having the capacity to absorb liquids while maintaining a suitable degree of mechanical strength. Furthermore, the present invention is generally directed to methods for making and using the foregoing devices and materials.

Mechanically strong absorbent non-woven fibrous mats

Embodiments relate to amino acid-based poly(ester urea)s with amino acid residues selected L-leucine, L-isoleucine, L-valine or combinations thereof. The amino acid-based poly(ester urea)S may optionally include a second amino acid residue selected from proteinogenic amino acids and non-proteinogenic amino acids. The amino acid-based poly(ester urea)s are particular useful for the preparation of vascular grafts. Due to the biocompatibility of the amino acid-based poly(ester urea)s, vascular grafts prepared from amino acid-based poly(ester urea)s with small internal diameters (i.e. less than 5 mm) may be prepared and inserted into a patient or animal, and provide a substantial decrease in the risk of failure compared to conventional polymers used in vascular grafts.

Resorbable, amino acid-based poly(ester urea)s scaffold for vascular graft tissue engineering

The present invention is generally directed to flexible ceramic fibers and to methods for making same. In one embodiment, the present invention relates to flexible ceramic fibers that are heat and chemical resistant, and to a method for making same. In another embodiment, the present invention relates to flexible ceramic nanofibers, and to a method for making same. In still another embodiment, the present invention relates to electrospun flexible ceramic nanofibers, products that include such fibers, and to methods of making same.

Flexible ceramic fibers and a process for making same

The invention provides high enzyme loading nanofibers and processes utilized in their fabrication, the nanofibers suitable for use as a new class of highly sensitive and stable biosensors capable of monitoring glucose at low levels. The biosensors, comprising nanofiber enzyme materials fabricated from organic solvent-based polymer-enzyme systems, can be used effectively in non-invasive transdermal biosensing applications.

Nanofibers with high enzyme loading for highly sensitive biosensors

The present invention generally relates to a device for measuring characteristics of polymeric fluids (semi-dilute and concentrated polymer solutions and melts) in extremely strong elongational flows. In one embodiment, the present invention relates to a device for measuring characteristics of polymeric fluids (semi-dilute and concentrated polymer solutions and melts) in extremely strong elongational flows in spinning jets and/or electrified jets. In another embodiment, the present invention relates to a method for determining the elastic modulus and the relaxation time of a polymeric fluid. Also, the present invention enables one to determine and/or measure the primary parameters needed to describe a viscoelastic material.

Method of characterization of viscoelastic stress in elongated flow materials

A nanofiber-reinforced composition suited to applying to a wound site in a human body includes a carrier liquid and nanofibers dispersed therein in the carrier liquid. The viscosity of the composition is such that it is able to be applied through a tube yet adhere proximate the wound site to provide a barrier layer which assists in healing of the wound by spacing it from neighboring organs.

Nanofiber-reinforced composition for application to surgical wounds

The present invention relates to a method for producing hybrid materials of thin polymer films with single, laminated, complete and/or partially embedded nanofibers to obtain products with unique functional properties. In one embodiment, the present invention involves a method that comprises the combination of two process technologies; a thin film solution casting process (tape casting, solvent casting) and an electrospinning process, in order to produce hybrid materials of thin polymer films with single, laminated, completely and/or partially embedded electrospun nanofibers to obtain products with unique functional properties. In another embodiment of the present invention, fibers and/or nanofibers of a chosen material are spun directly on to substrates of polymer solutions and/or monomers solutions, were such solutions are located on a carrier belt that is electrically and/or ionically conductive.

Hybrid manufacturing platform to produce multifunctional polymeric films

An apparatus and method for making coiled and buckled electrospun fiber including (a) providing a solution of a polymer in an organic solvent and a device for electrospinning fiber; b) subjecting the polymer solution to an electric field such that at least one fiber is electrospun; (c) subjecting the so formed fiber to electrical bending and mechanical buckling instability to hereby form a coiled and buckled fiber; (d) collecting the at least one fiber on a collector, such that a fiber structure is produced.

Method of making coiled and buckled electrospun fiber structures

The present invention relates to structures that contain one or more fiber and/or nanofiber structures where such structures can be formed on a wide variety of structures or surfaces (e.g., asperities, flat surfaces, angled surface, hierarchical structures, etc.). In one embodiment, the present invention relates to a process for forming one or more fibers, nanofibers or structures made therefrom on a wide variety of structures or surfaces (e.g., asperities, flat surfaces, angled surface, hierarchical structures, etc.). In another embodiment, the present invention relates to a process for forming one or more fibers, nanofibers or structures made therefrom on a wide variety of structures or surfaces (e.g., asperities, flat surfaces, angled surface, hierarchical structures, etc.) where such fibers and/or structures are designed to sequester, carry and/or encapsulate one or more substances. In still another embodiment, the present invention relates to structures that contain one or more fiber and/or nanofiber structures on asperities where the nanofiber and/or fiber structures are designed to sequester, carry and/or encapsulate one or more substances.

Electrospun structures and methods for forming and using same

A fibrous assembly is provided for performing site-specific chemistry. In general the present invention provides a fibrous assembly comprising a first fiber that sequesters a first reactive component; and a second fiber that sequesters a second reactive component, wherein at least the first or second fiber releases its reactive component when the fiber is in the presence of a releasing agent, and wherein when the at least first or second fiber releases its reactive component, the first and second reactive components react with each other to form a reaction product. Related methods of manufacture and use are also provided.

Sequestered reactive materials

The present invention includes embodiments that generally relate to methods and devices for control of electrospinning processes. Some embodiments include constant current electrospinning jets. Other embodiments include pressure control using a system of valves in fluid communication with the electrospinning fluid. Still other embodiments include control of one or more physical parameters.

Electrospinning control for precision electrospinning of polymer fibers

The present invention relates to methods and apparatus for removing water and/or water-based compounds from organic liquids/fluids. In one embodiment, the present invention relates to methods and apparatus that utilize fibrous media that contains, is impregnated, or is formed from at least one super absorbent compound, where the fibrous media is formed from nanofibers.

Method for removing water from an organic liquid

The invention relates to a novel method for electrospinning fibers wherein the fiber-spinning solution is infused with gas bubbles which travel through the electrospinning fluid, causing the bubbles to be coated with electrospinning solution. The coated bubbles, in turn, in response to an applied electrical force, generate jets of the electrospinning fluid that travel away from the bubble surface. The invention further relates to the fibers formed by this bubble-jet process and to products made therefrom.

Bubble launched electrospinning jets

Growing community of inventors

Akron, OH, United States of America

Darrell H Reneker