Medtronic, Inc.

Alza Corporation

Warsaw Orthopedic, Inc.

Medtronic Vascular, Inc.

Patrick T. Cahalan

Darrel F. Untereker

Joseph B. Phipps

Kenneth R. Brennen

Darrel F Untereker

Joseph B Phipps

Gary A Lattin

Arthur J Coury

Ann M Crespi

Paul M Skarstad

Kimberly A Chaffin

Xiangji Chen

Eric J Fogt

Gary M Phillips

Matthew Jolly

John Daniel Norton

Joseph F Lessar

Suping Lyu

Marye S Norenberg

Thomas P Grailer

Peter L Thor

Zhaoxu Wang

Greg C Marik

Patrick T Cahalan

Mark E Meyerhoff

Matthew J Birdsall

Donald R Merritt

Jeffrey W Allen

Michael Krivoruchko

Kenneth R Brennen

Randall V Sparer

Naim S Istephanous

Carlos M Duran

Jenn-Feng Yan

Hong S Shim

Brett R Vegoe

Julie A Alkatout

Richard Francis

Yan Jenn-Feng

Adam J Buckalew

Elizabeth A Ebner

A modified polyisobutylene-based polymer, method of making, and a medical device that includes such polymer, wherein the modified polyisobutylene-based polymer includes urethane, urea, or urethane-urea groups, hard segments, and soft segments, wherein the soft segments comprise phenoxy-containing polyisobutylene residues, and the hard segments include diisocyanate residues and optionally chain extender residues.

Modified polyisobutylene-based polymers, methods of making, and medical devices

Medical leads, such as medical electrical leads and medical neurological leads, that include a polymeric material that includes a silicone-urethane-containing polymer having improved hydrolytic stability.

Medical leads

Wet-tantalum capacitors used in a medical device are charged to and maintained at a maintenance voltage between full energy charges so that deformation in the wet-tantalum capacitor is substantially inhibited.

Method of maintaining wet-tantalum electrolytic capacitors

A balloon-expandable stent formed from a customized alloy formulation. The stent alloy has a either a high, variable or no work hardening rate, very high modulus of elasticity (Young's modulus), and a low yield point. A stent constructed of a material with this combination of properties undergoes significant plastic deformation upon deployment in vivo to its implantation diameter and exhibits minimum recoil for better sizing. The plastic deformation also raises the subsequent yield point of the stent material resulting in a stronger stent upon implantation that is more resistant to vascular loading.

Customized alloys for stents

This invention relates to an implantable medical device to treat a patient. The implantable device can be an orthopedic device such as a spinal implant including, but not restricted to, a disc or nucleus pulposus prosthesis, a spinal rod assembly, or a bone fixation plate. The orthopedic device can be formed to include a metal matrix composite that provides enhanced wear and diagnostic imaging techniques. In other forms, the present invention provides an implantable medical device that includes a porous metal matrix composite that can deliver a therapeutic composition to a patient. In still other forms, the present invention provides an implantable electrical device or lead formed to include a metal matrix composite that provides lower polarization and interfacial impedance and allows enhanced sensing of the physiological signals.

Implants based on engineered metal matrix composite materials having enhanced imaging and wear resistance

Implantable medical devices (IMDs) and their various components, including flat electrolytic capacitors for same, and methods of making and using same, particularly an improved electrolytic capacitor with optimized ESR and anode layer surface area. An electrode stack assembly and electrolyte are located within the interior case chamber of a hermetically sealed capacitor case. The electrode stack assembly comprises a plurality of capacitor layers stacked in registration upon one another, each capacitor layer comprising a cathode layer having a cathode tab, an anode sub-assembly comprising at least one anode layer having an anode tab, and a separator layer located between adjacent anode and cathode layers, whereby all adjacent cathode layers and anode layers of the stack are electrically insulated from one another by a separator layer. Anode terminal means extend through the capacitor case side wall for electrically connecting a plurality of the anode tabs to one another and providing an anode connection terminal at the exterior of the case. Cathode terminal means extend through or to an encapsulation area of the capacitor case side wall for electrically connecting a plurality of the cathode tabs to one another and providing a cathode connection terminal at the exterior of the case. A connector assembly is electrically attached to the anode connection terminal for making electrical connection with the anode tabs and to the cathode connection terminal for making electrical connection with the cathode tabs. The anode layers are formed of one or more partially through-etched anode sheet bearing an oxide layer and formed with a plurality of punctures therethrough.

Implantable medical device having flat electrolytic capacitor formed with partially through-etched and through-hole punctured anode sheets

Implantable medical devices (IMDs) and their various components, including flat electrolytic capacitors for same, and methods of making and using same, particularly an improved electrolytic capacitor with optimized ESR and anode layer surface area. An electrode stack assembly and electrolyte are located within the interior case chamber of a hermetically sealed capacitor case. The electrode stack assembly comprises a plurality of capacitor layers stacked in registration upon one another, each capacitor layer comprising a cathode layer having a cathode tab, an anode sub-assembly comprising at least one anode layer having an anode tab, and a separator layer located between adjacent anode and cathode layers, whereby all adjacent cathode layers and anode layers of the stack are electrically insulated from one another by a separator layer. Anode terminal means extend through the capacitor case side wall for electrically connecting a plurality of the anode tabs to one another and providing an anode connection terminal at the exterior of the case. Cathode terminal means extend through or to an encapsulation area of the capacitor case side wall for electrically connecting a plurality of the cathode tabs to one another and providing a cathode connection terminal at the exterior of the case. A connector assembly is electrically attached to the anode connection terminal for making electrical connection with the anode tabs and to the cathode connection terminal for making electrical connection with the cathode tabs. The anode layers are formed of one or more nonthrough-etched anode sheet bearing an oxide layer and formed with a plurality of punctures therethrough.

Implantable medical device having flat electrolytic capacitor formed with nonthrough-etched and through-hole punctured anode sheets

A band-shaped annuloplasty device (e.g., C- or D-shaped ring) that is relatively rigid during handling and implantation and becomes relatively complaint after implantation. Preferably, the device includes a core material that softens after implantation.

Rigid annuloplasty device that becomes compliant after implantation

Improved methods of ionophoretic drug delivery are described. By the intentional selection of drug(s) with specific characteristics, of ionotophoresis device, components or both permits the efficiency of drug delivery is increased.

Iontophoretic drug delivery

Iontophorett drug delivery

An improved iontophoresis electrode employing a current distributing member and a drug reservoir containing an ionic drug. The drug reservoir is applied to the skin of a patient, and includes a charge selective ion permeable membrane adapted to contact the skin, through which the ionic drug is delivered.

Iontophoresis electrode

Growing community of inventors

Oak Grove, MN, United States of America

Darrel F Untereker