Lifeassays Ab

Chemel Ab

The European Institute of Science Ab

Lifeassays Ab (publ)

Ab Implementa Hebe

European Institute of Science

Dario Kriz

Kirstin Ann Kriz

Margareta Krook

Christer Ljung

Karin Marie Berggren

Sarah Fredriksson

Kirstin Kriz

The present invention generally relates to the determination of an analyte concentration (quantitative determination) or whether an analyte threshold level has been passed (qualitative determination) in a biological sample through employment of a disposable analytical microprocessor device. The device can include a batch-specific, self-executable algorithm for the calculation of the analyte concentration.

Disposable analytical microprocessor device

A device for biochemical processing and analysis of a measured sample volume of a sample is described. The device is characterized in that it consists of a sealed vessel () and that it comprises at least one thin pierceable membrane () through which a capillary tube () containing said measured sample volume of a sample can pass into said sealed vessel (). Said sealed vessel () further contains at least one biochemically reactive substance () and a liquid (). A method, wherein the device according to the invention is used for analysis, is also described.

Device for biochemical processing and analysis of a sample

A device including a sample compartment, a coil and an arm for mechanical manipulation of a sample vessel placed in the sample compartment and containing a sample is described. In at least one embodiment, the coil is surrounding the sample compartment and the sample compartment has an opening for insertion and removal of the sample vessel. A method, using the device according to at least one embodiment of the invention for detection of magnetic permeability, relative magnetic permeability or relative magnetic susceptibility, is also described.

A device for detection of magnetic permeability &#x3bc; or, alternatively, relative magnetic permeability &#x3bc;or, alternatively, relative magnetic susceptibility (&#x3bc;&#x2212;1) of a sample, wherein said device contains a sample chamber and at least two coils, one coil surrounding said sample chamber and one coil placed so as to be in thermal contact by being physically connected to the material which constitutes the sample chamber, but without surrounding the cavity of the sample chamber, said sample chamber having at least one opening for introduction of a sample or a sample container holding a sample, said device also provided with an electronic circuit which measures the difference in inductance between the two coils.

Drift compensated magnetic permeability detector

A device and method are provided for the reliable calibration of detector units for the detection of low-molecular substances in a liquid flow.

Calibratable flow detector

A new device for therapeutic influence, change, decomposition of various biological structures in vivo or in vitro by means of an externally applied alternating magnetic gradient field is described.

Device for therapeutic purposes on human tissue, for influencing injected magnetic particles with an alternating electro-magnetic gradient field

A chemical sensor selectively detects an analyte in a solution. The sensor comprises a flow-through chamber, a selective membrane, a transducer, an inlet for a liquid flow containing a recognition element, and an outlet. To detect an analyte in a solution, a recognition element is contacted with the solution containing the analyte via a selective membrane. This results in a response detectable by a transducer. The recognition element is injected into a flow, and the flow is passed into a flow-through chamber comprising the transducer and the selective membrane, where it contacts the analyte passing from the solution outside the chamber. The recognition element and the analyte interact to provide a signal that is detected by the transducer. The chemical sensor is used for detecting analyte(s) in a reactor system, a flow system or in an in vivo system.

Chemical sensor and use thereof

The present invention relates to a device in performing a process in a process medium by varying the parameters of said process medium over time in a laboratory scale, according to a predetermined scheme. The device comprises at least one reaction receptacle, a heat transfer plate, a peltiere element, a temper sensor, a magnetic stirrer and a data processing unit. The data processing unit is adapted to send out signals to the peltiere element in response to incoming signals from the temperature sensor. The invention further relates to a method for controlling the data processing unit.

Device and method for performing a process in a process medium

A disposable body fluid or tissue collection vial is disclosed. The vial has a sample accessing tool and a sample delivery member for dispensing a sample of body fluid or tissue into a reagent. The vial also has a base, a sample delivery sleeve, a sample accessing sleeve, and a cap. The sample delivery sleeve detachably attaches to the base, the sample accessing sleeve detachably attaches to the sample delivery sleeve, and the cap detachably attaches to the sample accessing sleeve. The base may contain one or more reagents suitable for diagnostic or other uses.

Disposable test vial with sample delivery device for dispensing sample into a reagent

A chemical sensor (,) for selectively detecting an analyte in a solution as described. The sensor comprises a flow-through chamber (,), a selective membrane (,), a transducer means (,), an inlet (,) for a liquid flow containing a recognition element, and an outlet (,). There is also described a method of selectively detecting an analyte in a solution, wherein a recognition element is contacted with the solution containing the analyte via a selective membrane, said contact resulting in a response detectable by transducer means. The recognition element is injected into a flow, the flow is passed into a flow-through chamber comprising a transducer means and the selective membrane, where it is contacted with the analyte passing from the solution outside the selective membrane, whereby the recognition element and the analyte interact to provide a signal which is detected by the transducer means. The use of the chemical sensor for detecting of analyte(s) in a reactor system, a flow system or in an in vivo system is also described.

Use of a chemical sensor

A system for very sensitive detection and/or quantification of an analyte is disclosed. The system is based on an interaction, such as specific binding or competitive displacement from a ligand, between an analyte and a ferromagnetic marker. The great difference in magnetic permeability between the ferromagnetic marker and the background allows detection of very small quantities of analyte, based on the marker's induction of a changed magnetic permeability for the sample being measured.

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Höör, Sweden

Dario Kriz