Jiangsu Academy of Agricultural Sciences

Daohua Zhang

Zhanwei Wang

Li Wang

Qiyan Xiong

Zhixin Feng

Yuan Gan

Maojun Liu

Yuzi Wu

Yanna Wei

Yun Bai

Haiyan Wang

Fangfang Bai

Dongxia Liu

Guoqinq Shao

Lizhong Hua

Disclosed are an attenuated live vaccine against mycoplasmal pneumonia of swine (MPS) and use thereof. In the present invention, pathological lung tissues of swine having typical(Mhp) infection and no obvious other pathogenic infections are screened, and subcultured 100 generations in lungs of newborn rabbits; then, Mhp strains are isolated and serially subcultured in a medium; and the Mhp strain AN306 is obtained by screening a plurality of strains, which is deposited with an accession number: CCTCC NO. M2012431. Also disclosed is a live vaccine formulation against MPS prepared on the basis of the attenuated strain and comprising live attenuated strain, a pharmaceutically acceptable carrier or excipient, and optionally an adjuvant and immunogens of other pathogens.

Attenuated live vaccine against mycoplasmal pneumonia of swine (MPS) and use thereof

Growing community of inventors

Nanjing, China

Daohua Zhang