Cardiac Pacemakers, Inc.

Boston Scientific Scimed, Inc.

Danielle Frankson

Joseph T Delaney, Jr

David R Wulfman

Mary M Byron

Adam McGraw

Angelo Fruci

Gregory J Sherwood

Adeniyi O Aremu

Kenneth L Gunter

Mark D Wood

James P Rohl

Paul Daniel Aquilino

Benn Horrisberger

James A Klos

Lance Adam Freeseman

Matthew P Jones

Jeffrey E Stahmann

Keith R Maile

Michael John Kane

David J Ternes

Benjamin J Haasl

Brian L Schmidt

Arthur J Foster

Joel T Eggert

Craig Michael Stolen

Dana Sachs

Lauren Lydecker

Sarah Melissa Gruba

Robert Allen Jones

Bryan J Swackhamer

Thomas Lee Williams

Kurt G Koubal

Edward J Maierhofer

Erin Kristen Webb

Joel Becklund

Joseph Thomas Delanely, Jr

Poorva Rajguru

Kate Jensen

Gregory Sallee

Patrick A Merriam

Kylee M Lersch

Joseph Thomas Delaney, Jr

Lauren Sfakis Lydecker

David Robert Wulfman

Kate Jansen

Jr Joseph T Delaney

A medical device that includes a body and a polymer matrix over the body. The polymer matrix includes a plurality of fibers defining a plurality of pores to permit tissue growth therethrough. The medical device includes a bio-adhesive coating at least partially covering the polymer matrix.

Medical implantable devices and methods of using the same

According to one aspect, a visualization device may include an image sensor, a lens for focusing light onto the image sensor, a first end, a second end opposite the first end, a lateral wall surface extending between the first end and the second end, and a coating on the lateral wall surface. The coating may include at least one of an electrically-insulating layer and a light-blocking layer, and may be deposited on the lateral wall surface using, for example, physical vapor deposition (PVD).

Visualization device and related systems and methods

An implantable antibacterial barrier device for an elongated medical device, the elongated medical device configured to extend from a first site, through a second site, to a third site. The implantable antibacterial barrier device includes a housing configured to be disposed at the first site, a working electrode configured to be disposed at the second site, and a reference electrode configured to be disposed at the first site. The housing includes barrier circuitry. The working electrode electrically is coupled to the barrier circuitry. The reference electrode is electrically coupled to the barrier circuitry. The barrier circuitry is configured to selectively maintain the working electrode at a negative electrical potential relative to the reference electrode to form an antibacterial barrier.

Implantable devices and methods for control of bacterial infections

An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.

Durable antimicrobial layer for implantable medical devices

A method for making an insertable or implantable medical device including a lubricous coating on a silicone substrate includes treating the silicone substrate with an atmospheric plasma at about atmospheric pressure, the atmospheric plasma formed from a noble gas; applying a solution directly to the treated silicone substrate, the solution including a thermoplastic polyurethane; and heating the silicone substrate and the applied solution to form the lubricous coating on the silicone substrate.

Lubricous silicone

A coating for a metal surface, the coating including poly(ethylene glycol) disposed on and covalently bonded directly to at least a portion of the metal surface, and a functional group grafted to at least a portion of the poly(ethylene glycol). The functional group is one of a bioactive functional group and an antimicrobial functional group.

Functionalized PEG for implantable medical devices

An implantable medical electrical lead is connectable to an electrical header of an implantable pulse generator. The lead includes a lead body, at least one electrode, a lead terminal, and a lead boot. The lead body extends from a proximal end to a distal end. The at least one electrode is disposed at the distal end of the lead body. The lead terminal is disposed at the proximal end of the lead body and configured to connect the lead to the electrical header. The lead boot is formed of an elastic polymer infused with at least one antibiotic drug. A portion of the lead boot is configured to be disposed within the electrical header when the lead is connected to the electrical header.

Infection fighting drug eluting lead boot

An electrode for cardiac signal sensing includes an intermediate layer, an iridium-containing layer, an iridium oxide layer, an insulating polymer layer, and a conductive layer formed on a flexible polymer substrate. The intermediate metal layer has a first portion and a second portion, and is formed on the conductive layer. The iridium-containing layer includes at least 50 wt. % iridium and has a first portion and a second portion, and is formed on the first portion of the intermediate metal layer. The iridium oxide layer is formed on the first portion of the iridium-containing layer. The insulating polymer layer is formed on the second portion of the intermediate metal layer and the second portion of the iridium-containing layer. The iridium-containing layer is not formed on the second portion of the intermediate metal layer; and the iridium oxide layer is not formed on the second portion of the iridium-containing layer.

Flexible electrode for cardiac sensing and method for making

An implantable drug eluting medical device includes a polymer substrate having a surface, a first plurality of nanofibers, and at least one antimicrobial drug. Each of the first plurality of nanofibers includes a first portion interpenetrated with the surface of the substrate to mechanically fix the nanofiber to the substrate, and a second portion projecting from the surface. The at least one antimicrobial drug is disposed within or among the second portion of the first plurality of nanofibers.

Infection fighting drug eluting device

An implantable leadless pacing device may comprise a power source and circuitry operatively coupled to the power source. The circuitry configured to pace a patient's heart and/or sense electrical activity of the patient's heart. A housing may at least partially enclose the circuitry. The pacing device may further include a first electrode secured relative to the housing and a fixation mechanism secured relative to the housing. The fixation mechanism may comprise a plurality of tines configured to move between an elongated delivery configuration and a curved deployed configuration. Each tine of the plurality of tines may include a radiopaque material.

Fixation methods for leadless cardiac devices

A coating for a roughened metal surface of an implantable medical device includes a poly(ethylene glycol) disposed on at least a portion of the roughened metal surface, wherein the poly(ethylene glycol) is covalently bonded directly to the roughened metal surface.

Hydrophilization and antifouling of enhanced metal surfaces

An implantable medical device (IMD) may include an outer housing having a titanium outer surface, the titanium outer surface including a plurality of titanium atoms. A tissue growth-inhibiting layer may extend over the titanium outer surface. In some cases, the tissue growth-inhibiting layer may include a plurality of polyethylene glycol molecules, at least some of the plurality of polyethylene glycol molecules covalently bonded via an ether bond to one of the plurality of titanium atoms.

Retrievability for implantable medical devices

A method for producing an antimicrobial coating on a surface. The method includes mixing a parylene dimer and an antimicrobial agent to form a mixture, heating the mixture to sublimate the parylene dimer and suspend the antimicrobial agent within the sublimated parylene dimer, pyrolyzing the sublimated parylene dimer to form a parylene monomer while the antimicrobial agent is suspended within the parylene monomer, and condensing the parylene monomer and the antimicrobial agent together on the surface to polymerize the parylene monomer and form a coating containing a parylene polymer and the antimicrobial agent.

Polymer coating with antimicrobial materials and methods for producing

Growing community of inventors

Dayton, MN, United States of America

Danielle Frankson