Asher Biotherapeutics, Inc.

Danielle C Pappas

Wei Chen

Yik Andy Yeung

Henry C Nguyen

Ivana Djuretic

Irene Ni

Terrence Park

Paul Bessette

Sherman Michael Chin

Kelly Dare Moynihan

Provided herein are anti-CD8 antigen binding molecules and fusion polypeptides comprising the CD8 antigen binding molecules for selectively modulating the function of CD8+ T cells over other immune cells. In addition, the present disclosure also provides polynucleotides encoding the disclosed antigen binding molecules and fusion polypeptides, and vectors and host cells comprising such polynucleotides. The present disclosure further provides methods for producing the antigen binding molecules and fusion polypeptides, pharmaceutical compositions comprising the same, and uses thereof.

Fusions with CD8 antigen binding molecules for modulating immune cell function

Growing community of inventors

San Mateo, CA, United States of America

Danielle C Pappas