Koninklijke Philips Corporation N.v.

Philips Intellectual Property & Standards Gmbh

Danielle Beelen

Martin Ouwerkerk

Jochen Keupp

Wilhelmus Cornelis Keur

Holger Gruell

Henricus Albertus Maria Van Hal

Dirk Burdinski

Sander Langereis

Described are drug carriers useful in magnetic resonance imaging (MRI)-guided drug release comprising a shell capable of releasing an enclosed biologically active agent as a result of a local stimulus, e.g. energy input, such as heat, wherein the shell encloses aF MR contrast agent. Preferably, the carrier also acts as a contrast enhancement agent for MRI based on the principle of Chemical Exchange-dependent Saturation Transfer (CEST). To this end the shell encloses a cavity that comprises a paramagnetic chemical shift reagent, a pool of proton analytes, and theF contrast agent, and wherein the shell allows diffusion of the proton analytes.

Drug carrier providing MRI contrast enhancement

Disclosed is a hydrogen storage material comprising a magnesium hydride. Said magnesium is stabilized in the fluorite structure. Preferably, the magnesium is at least partly substituted by an element such that the magnesium hydride is stabilized in the fluorite structure. In an advantageous embodiment, the hydrogen storage material also comprises a catalytically active material. Furthermore, an electrochemically active material, as well as an electrochemical cell comprising the above hydrogen storage material are disclosed.

Hydrogen storage material with high storage capacity

Growing community of inventors

Eindhoven, Netherlands

Danielle Beelen