Vicuron Pharmaceuticals Inc.

Oscient Pharmaceuticals Corporation

Naicons S.c.a.r.l.

Daniela Jabes

Giorgio Mosconi

Martin Stogniew

Adriano Malabarba

Marco Cavaleri

Timothy Henkel

Richard J White

Richard F Labaudiniere

Gabriela Romano

Timothy S Leach

Steven M Rauscher

Gabriella Romano'

Use of the compound of formula (I) and the pharmaceutically acceptable addition salts thereof for the manufacture of a medicament for topical treatment or 5 prevention of acne formula (I) wherein: R represents methoxymethyl, R1 represents methyl, Rz represents methyl, Y represents the group formula (II) The compound of formula (I) and the pharmaceutically acid addition salts thereof show selective activity againstand are suitable for use in a method of treatment or prevention of acne. 

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The invention features a method of treating or preventing a disease associated with the use of antibiotics in a patient in need thereof by administering to the patient ramoplanin in an amount and for a duration effective to treat said disease. The disease may be caused, for example, by the presence of a bacterium such as enterotoxin producing strains of, or

Use of ramoplanin to treat diseases associated with the use of antibiotics

The invention provides methods and compositions for treatment of bacterial infections. Methods of the invention include administration of dalbavancin for treatment of a bacterial infection, in particular a Gram-positive bacterial infection of skin and soft tissue. Dosing regimes include once weekly administration of dalbavancin, which often remains at therapeutic levels in the bloodstream for at least one week, providing prolonged therapeutic action against a bacterial infection.

Stable pharmaceutical compositions of dalbavancin and methods of administration

Methods of administering dalbavancin for treatment of bacterial infections

Growing community of inventors

Cassina Rizzardi, Italy

Daniela Jabes