USA As Represented by Secretary of the Navy

Science Applications International Corporation

Daniel Zabetakis

Walter J Dressick

Paul E Schoen

George P Anderson

Ellen R Goldman

Joel M Schnur

David A Stenger

Ronald R Price

Scott A Trammell

Robert F Brady, Jr

Jinny Lin Liu

Kendrick Turner

Ann E Mera

Dana Leamann

Bor-Sen Chiou

P Audrey Brozozog Lee

Jasenka Verbarg

Michael A Dinderman

Alok Singh

David Kurt Gaskill

Rachael L Myers-Ward

Scott G Walton

Sandra C Hangarter

Scott M Browning

Jonas K Lodge

An electrochemical cell includes a working electrode in contact with an aqueous electrolyte solution, a counter electrode in contact with the aqueous electrolyte solution, and a reference electrode in contact with the aqueous electrolyte solution. The working electrode comprises a plasma modified epitaxial synthesized graphene surface fabricated on SiC.

Plasma modified epitaxial fabricated graphene on SiC for electrochemical trace detection of explosives

A single-domain antibody (sdAb) is produced by causing a bacteria to express the sdAb into cytoplasm of the bacteria, wherein the sdAb is expressed as a fusion protein with the acid tail of &#x3b1;-synuclein. In embodiments, the protein is free of a periplasmic location tag. Such antibodies have the unexpected ability to refold after thermal denaturation.

Single-domain antibody fusion proteins with the acid tail of alpha-synuclein

A nucleic acid encodes a single-domain antibody (sdAb) is produced by causing a bacteria to express the sdAb into cytoplasm of the bacteria, wherein the sdAb is expressed as a fusion protein with the acid tail of &#x3b1;-synuclein. In embodiments, the protein is free of a periplasmic location tag. Such antibodies have the unexpected ability to refold after thermal denaturation.

Nucleic acids for single-domain antibodies with thermal stability under cytoplasmic expression

Methods of producing a single-domain antibody (sdAb) include causing a bacteria to express the sdAb into cytoplasm of the bacteria, wherein the sdAb is expressed as a fusion protein with the acid tail of &#x3b1;-synuclein; and then purifying the sdAb, wherein the fusion protein is expressed free of a periplasmic location tag. Such antibodies have the unexpected ability to refold after thermal denaturation.

Single-domain antibodies with improved thermal stability under cytoplasmic expression

Described herein are new recognition elements (antibodies or functional fragments thereof) that effectively bind to trinitrotoluene (TNT). Also disclosed is a single chain fragment recognition element.

Antibody and recombinant derivative for the detection of trinitrotoluene

Described herein is the development of recombinant single domain antibodies, also known as nanobodies, that may provide better therapeutic results or be useful for diagnostic applications of B-cell lymphomas, or in other applications where an antibody to CD20 may be useful.

Single domain antibodies that bind to human CD20

Described herein is an approach using inexpensive, disposable chemical sensor probes that can be mounted on a small unmanned aerial vehicles (UAVs) and used to analyze a site (such as one known or suspected to contain explosive residue, spilled material or contaminated soil) without the need for a person to conduct ground operations at the site. The method involves contacting a soil or a surface with a filter paper wetted with a solvent, then subjecting the filter paper to spectroscopy, thus detecting a possible variation indicative of one or more analytes, wherein the solvent is a deep eutectic solvents consisting of a mixture of ethylene glycol and choline chloride.

Spectroscopic method for the extraction and electrochemical detection of explosives and explosive components in soils using filter paper, and electrolyte

Described herein is an approach using inexpensive, disposable chemical sensor probes that can be mounted on a small unmanned aerial vehicles (UAVs) and used to analyze a site (such as one known or suspected to contain explosive residue, spilled material or contaminated soil) without the need for a person to conduct ground operations at the site. The method involves contacting a soil or a surface with a filter paper wetted with a solvent, then subjecting the filter paper to voltammetry and/or spectroscopy, thus detecting a possible variation indicative of one or more analytes, wherein the solvent is the deep eutectic solvent consisting of a mixture of ethylene glycol and choline chloride.

Unmanned aerial vehicle system for the extraction and electrochemical detection of explosives and explosive components in soils using filter paper and electrolyte

Described herein is an approach using inexpensive, disposable chemical sensor probes that can be mounted on a small unmanned aerial vehicles (UAVs) and used to analyze a site (such as one known or suspected to contain explosive residue, spilled material or contaminated soil) without the need for a person to conduct ground operations at the site. The method involves contacting a soil or a surface with a filter paper wetted with a solvent, then subjecting the filter paper to voltammetry and/or spectroscopy, thus detecting a possible variation indicative of one or more analytes, wherein the solvent is selected from the group consisting of polar aprotic or protic solvents having a boiling point of at least 100&#xb0; C., room temperature ionic liquids, and deep eutectic solvents.

Method for the extraction and electrochemical detection of explosives and explosive components in soils using electrodes, filter paper, and electrolyte

The present invention is generally directed to an artificial dielectric composite having an electrically non-conducting substrate, an electrically non-conducting pattern on the substrate, and an electrically conducting coating on the pattern. The substrate may be a textile such as paper. The electrically non-conducting pattern may comprise palladium. A direct-write device, such as an inkjet printer, may be used to print the pattern onto the substrate. The electrically conducing coating may comprise nickel, gold, palladium, cobalt, iron, copper, or any combination thereof. Also disclosed is the related method of making the artificial dielectric composite.

Artificial dielectric composites by a direct-write method

The present invention is directed to a method for making a conformal antenna on a surface by providing a composition comprising a polymer matrix and a plurality of metalized tubules and applying the composition to the surface as two parallel wires connected at their ends to make a closed loop with one of the parallel wires broken in the middle. Also disclosed is an alternate method for making a conformal antenna on a surface by spraying a first material comprising a polymer matrix onto the surface and simultaneously spraying a second material comprising a plurality of metalized tubules and a coagulant onto the surface, wherein the first and second materials mix together during the spraying. A further method for making a conformal antenna includes spraying a first material comprising a polymer matrix and a plurality of metalized tubules onto the surface and simultaneously spraying a second material comprising an aqueous electroless plating bath onto the surface, wherein the first and second materials mix together during the spraying.

Conductive microcylinder-based paints for integrated antennas

This invention pertains to a product and a method for preparing same. The product is an electrically conducting metallized fibers and a non-conducting composite containing the metallized fibers. In a preferred embodiment, the product is a composite of metallized cellulose fibers disposed in an electrically non-conducting matrix. The method includes the steps of hydrating cellulose fibers to prevent absorption of chemical reagents; activating the cellulose surface of the fibers for metal deposition; removing from the fibers excess activator and reagents used in the activation; drying the fibers to a free-flowing condition whereby the fibers acquire the color of the activator by virtue of its deposition on the fibers; metallizing the fibers to deposit thereon a metal capable of absorbing electromagnetic radiation; drying the metallized fibers whereby they are free-flowing; and forming a composite composed of an electrically non-conductive matrix having dispersed therein the matallized fibers.

Metallized fibers and method therefor

The present invention provides microwave attenuating, filled composite materials which contain a polymer or ceramic matrix and metallic tubules and processes for making the same and devices which contain such materials.

Microwave-attenuating composite materials, methods for preparing the same, intermediates for preparing the same, devices containing the same, methods of preparing such a device, and methods of attenuating microwaves

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Brandywine, MD, United States of America

Daniel Zabetakis