Bioquantetics, Inc.

Daniel Weihs

Edmond Rambod

Yacov Itzchak

Ari Shamiss

A method for the detection and localization of breast microcalcification through a precise method of ultrasound impacting and ultrasound frequency wave detection which will enable the system to detect not only if there is a microcalcification in the breast, but the precise location of the microcalcification and the mass of the microcalcification. The invention is also a method and system that provides bi-modal guided stimulation of a targeted mass within the breast to determine the location and nature of the microcalcification within the breast.

Application of image-based dynamic ultrasound spectrography (IDUS) in detection and localization of breast microcalcifcation

Using Image-based Dynamic Ultrasound Spectrography (IDUS&#xae;) technology, the intrabody monitoring and positioning of an inserted catheter is achieved by coupling a thin micron-size polymeric wire to the catheter with 100-500 micron metallic cylinder attached to the tip of the wire. The area of interest is imaged and subsequently stimulated using specialized stimulation schemes delivered by an imaging ultrasound transducer. The targeted metallic tip is stimulated and emanates a unique acoustic response (signature) corresponding to its mechanical and material properties. Because of the fundamental structural differences between the targeted metallic tip and its surroundings, its unique resonant frequency signature can be analyzed and differentiated relative to the surrounding soft tissue, the wire and the catheter itself so that the location of the catheter in the body can be determined.

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Haifa, Israel

Daniel Weihs