General Electric Company

Ge Precision Healthcare LLC

Daniel Richard Schneidewend

Adrian F Warner

Rodger F Schmit

Timothy P Stiemke

Claudio Patricio Mejia

Nicholas P Nekich

Hao Lai

Maxime Cazalas

Daniel J Nowicki

Linda Marie Helvick

James Vradenburg Miller

Joel Qiuzhen Xue

Nathan Dworshak

Patrick Thomas Moran

James M Peschke

Hans-Peter Stoll

Michael McOlash

Jeffrey Wayne Eberhard

Joseph Manak

Gary Secora

Sachin Vadodaria

Daniel P Mabini

Vivek Sachdev

Aaron James Hill

Angela Orentas

Roger F Schmit

David Allen Powell

Richard W Schefelker

Pat T Moran

Payam Karbassi

Venkat Krishnan

Mark Kohls

A system and method for evaluating blood flow in a vessel of a patient includes a catheter containing a first pressure sensor and a second pressure sensor and configured to simultaneously measure pressure data within a vessel on either side of a stenosis. Pressure data generated by the catheter includes a first series of pressure measurements from the first pressure sensor a second series of pressure measurements from the second pressure sensor. The system and method further includes a fractional flow reserve (FFR) calculation module executable on one or more processors and configured to calculate a stability index for each of two or more portions of the pressure data, wherein each stability index indicates at least one of heart rate stability and catheter stability for the respective portion of the pressure data. An optimal time window is identified based on the stability indexes for calculation of FFR based on the pressure data. A FFR value is then calculated based on the pressure data in the optimal time window.

System and method for evaluating blood flow in a vessel

A physiological data acquisition system includes at least one interface module and a base unit configured to communicatively connect to the at least one interface module to receive the physiological signals recorded by a catheter. Each interface module is formed by mating at least a first one of the two or more different personality modules to a dock. The dock has a multi-modal connection port configured to directly connect to a dock connector of any one of the two or more different personality modules so as to receive physiological signals therefrom. The first personality module includes a first catheter connector configured to receive a connection end of the catheter so as to receive physiological signals therefrom, and a first dock connector configured to connect to the multi-modal connection port of the dock so as to provide the physiological signals thereto.

Customizable interface system for invasive cardiology and electrophysiology

A system for analyzing noise in one or more electrophysiology studies is provided. The system includes at least one processor and at least one memory device. The memory device stores an application that adapts the at least one processor to: identify, based at least in part on a machine learning model, one or more noise fingerprints within data derived at least in part from one or more study signals acquired from one or more patients during the one or more electrophysiology studies.

System and method for analyzing noise in electrophysiology studies

In the present invention, a right leg drive RLD monitoring system is employed on a medical computing system/computer, such as an ECG, HEMO and/or EP monitoring, mapping and/or recording system, that includes a number of RLD circuits to be utilized for different procedures or monitoring states to be performed using the system. The RLD monitoring system operates to actively monitor and/or record the feedback voltage to the RLD isolated from the patient. Using the measured feedback voltage data, the RLD monitoring system can identify and determine if the RLD circuit in use is approaching saturation, has reached saturation and the duration the RLD circuit was in saturation. The RLD monitoring system can concurrently and/or subsequently select and/or provide selection information regarding an optimal RLD circuit to be utilized to most effectively perform the desired function of the RLD in the procedure being performed using the monitoring, mapping and/or recording system.

Quantification and of electrocardiogramag drive function system and method

In the present invention, a system and method for selection of an optimal catheter for use in a medical procedure relative to the anatomy of a patient includes the steps of providing a system including a scanning device capable of obtaining image data on a ROI within the anatomy of a patient and reconstructing a 3D image of the ROI from the image data, a display capable of illustrating the 3D image and a 3D catheter model, and a CPU operably connected to the scanning device and the display and operable to analyze the 3D image in comparison with the 3D catheter model, obtaining image data of the ROI of the patient, reconstructing a 3D image of the ROI from the image data and comparing the 3D catheter model with the 3D image of the ROI to determine the catheter with the optimal configuration for use in the procedure.

System and method for optimal catheter selection for individual patient anatomy

Quantification and qualification of electrocardiograph right leg drive function system and method

In the present invention, an interface control module for controlling a mapping/imaging/recording system is provided for placement on a catheter control handle. The interface control module includes control elements that are operably connected to the mapping/imaging/recording system in order to control various functions of the imaging/recording system relating to images represented on a display forming a part of the mapping/imaging/recording system. The interface control module can be integrated with the catheter control handle or can be formed as a separate component that is releasably attachable to the catheter control handle to enable a use to operate the mapping/imaging/recording system from the catheter control handle being utilized in an interventional medical procedure.

Catheter-based user interface device for remote control of display images

A system for evaluating blood flow in a vessel of a patient includes a catheter containing a first pressure sensor and a second pressure sensor and configured to simultaneously measure pressure data within a vessel on either side of a stenosis. Pressure data generated by the catheter includes a first series of pressure measurements from the first pressure sensor a second series of pressure measurements from the second pressure sensor. The system further includes an FFR calculation module executable on one or more processors and configured to calculate a stability index for each of two or more portions of the pressure data, wherein each stability index indicates at least one of heart rate stability and catheter stability for the respective portion of the pressure data. An optimal time window is identified based on the stability indexes for calculation of fractional flow reserve (FFR) based on the pressure data. An FFR value is then calculated based on the pressure data in the optimal time window.

In the present invention, a medical device authorization system is employed to associate software contained on a medical computing system/computer, such as an EP mapping and recording system, that pertains to a specific medical device, e.g., a transducer, connected to the computer such that the software is only utilized by the computer in conjunction with a catheter that is authorized for use with the computer. The authorization system utilizes an analog authorization waveform/signal that is mixed with the analog device/catheter measured signals transmitted to the computer. The authorization waveform distorts the measured signals in a manner that renders the signals able to be displayed by the system but unusable, unless the computer includes a signal filter operably connected to the device/transducer interface that is configured to remove the interfering authorization waveform from the measured signal.

Catheter authorization system and method

In the present invention, a catheter identification system for providing information about one or more attributes of a catheter connectable to an electrophysiology (EP) recording or mapping system includes a catheter, a resistor network operably connected to the catheter, the resistor network including at least one identification resistor and an identification resistor measurement circuit operably connected to the catheter and configured to send an identification signal through the at least one resistor in the resistor network to retrieve an altered identification signal from the identification resistor, where the altered identification signal provides information on an attribute of the catheter.

Passive catheter identification and self-configuration system

In the present invention, a system that has a navigation signal delivered by one of a signal or navigation catheter or treatment catheter as directed by a controller for detection by the other of the navigation catheter or the a treatment catheter to navigate the treatment catheter to a specific point or area of interest using the detected navigation signal is provided. The system is operable in a method to perform the above utilizing the mapping function of the electrophysiology mapping and/or recorder system to energize electrodes on either the navigation catheter or treatment catheter to direct the treatment catheter to the area, region or point of interest.

Intracardiac localization and guidance system and method

In the present invention, a system and method is provided for the self-certification of third party software products for use on medical products by the customer. The system enables the customer to test, qualify, and certify a third party software product for use on a controlled medical device independent of any testing or other intervention by the manufacturer. The system can be located on the particular medical device and provides internal testing and certification mechanisms to promote/authorize third party software products onto to the device/software authorization catalog, as well as notification to the manufacturer of the customer approved addition to the device certified third party software product catalog.

Method and system for user-verifiable certification of software for medical devices

A method of identifying gaps between electrophysiology (EP) ablation points may comprise: obtaining a plurality of ablation points recorded from a completed electrophysiology ablation procedure; digitally mapping the plurality of ablation points to an anatomical model corresponding to the completed electrophysiology ablation procedure; calculating ablation gap probability distributions for each of the plurality of ablation points based on ablation tolerance variables associated with each of the plurality of ablation points; and overlaying the ablation gap probability distributions on to the digitally mapped plurality of ablation points on the anatomical model. In this way, ablation gaps may be non-invasively identified prior to patient discharge, thereby allowing for further EP treatment to remove the ablation gaps while reducing readmission rates. Furthermore, by representing ablation points using calculated ablation burn density distributions and ablation gap probabilities, the accuracy of identifying ablation gaps may be increased.

Methods and systems for electrophysiology ablation gap analysis

An electrophysiology data acquisition system that receives physiological signals from at least one catheter includes an amplifier and at least one noise reduction circuit operatively connected to the amplifier and configured to cancel interference in the physiological signals from the catheter. A drive selection circuit is controllable to connect any one of two or more available electrodes to the noise reduction circuit such that the connected electrode becomes an equalization drive electrode for the catheter. An equalization control module is executable on a processor and configured to select the equalization drive electrode from the two or more available electrodes and to control the drive selection circuit to connect the selected equalization drive electrode to the noise reduction circuit.

Electrophysiology data acquisition system and method with differentiated equalization drive circuits

In the present invention, a haptic feedback module for use with a medical computer system employed in non-robotic interventional medical procedure is provided for placement on a catheter control handle. The haptic feedback module includes transducers that are operably connected to the computer system in order to enable the feedback module to provide haptic feedback to a user in response to sensor data and other information supplied to the computer system. The haptic feedback module is formed as a separate component that is releasably attachable to the catheter control handle to enable a user to receive the haptic feedback while retaining control of the catheter control handle being utilized in the interventional medical procedure.

Growing community of inventors

Wauwatosa, WI, United States of America

Daniel Richard Schneidewend