University of Southern California

The Population Council, Inc.

Daniel R Mishell, Jr

Robert M Nakamura

Harold A Nash

Paul G Stumpf

A method for direct serum assay of steroid hormones wherein the competition from binding protein, having an affinity for complexing with the steroid hormones, is significantly eliminated by adding to the serum an artificial compound which has a greater or equal affinity for the binding protein than do the steroid hormones, and which is not immuno-reactive with the steroid hormones. Because the compound is artificial, it is non-contaminating. Levonorgestrel and norethindrone as such compounds are disclosed.

Non-contaminating direct serum assay of steroid hormones

This invention relates to an improved intravaginal ring for use as a contraceptive comprising an inert elastomer core, a medicated layer encircling the core and an outer inert elastomer layer and method of manufacturing the intravaginal ring.

Growing community of inventors

Palos Verdes Estates, CA, United States of America

Daniel R Mishell, Jr