Genzyme Transgenics Corporation

Gtc Biotherapeutics, Inc.

Genzyme Transgenics Corporatiion

Daniel Pollock

Harry M Meade

Paul Ditullio

The invention provides, in part, methods for the production of proteins in a transgenic non-human mammal, wherein the proteins are transported from the blood to the mammary gland for secretion in milk. The transport of the protein to the mammary gland and/or milk is facilitated by binding to a transport receptor in the mammary gland.

Non-human transgenic mammal expressing a human FcRn on its mammary gland cells and expressing a transgenic protein-human Fc-domain fusion

A method for the production of monoclonal antibodies in mammal's milk through the creation of transgenic animals that selectively express foreign antibody genes in mammary epithelial cells.

Transgenic production of antibodies in milk

A method for the production of monoclonal antibodies in mammal's milk, through the creation of transgenic animals that selectively express foreign antibody genes in mammary epithelial cells.

Growing community of inventors

Medway, MA, United States of America

Daniel Pollock