Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno

Daniel Perez Calero

James Peter Robert Day

Marijn Sandtke

Tom Duivenvoorde

Jacobus Johannes Frederik Van Veen

Kees Moddemeijer

Jacobus Thomas Wilhelmus Elisabeth Vogels

Maarten J Scholtes-Timmerman

The present disclosure concerns a measuring probe () for non-invasive in vivo measurement of blood analytes () by Raman spectroscopy. The measuring probe () comprises a housing () having a skin engaging surface (). The housing () comprises a first optical system () arranged for providing source light () to the skin engaging surface () for penetrating a subject's skin () by said source light () for interacting with the blood analytes (). The housing () further comprises a second optical system () arranged for capturing scattered Raman light () from the blood analytes () for measurement of the blood analytes (). The first optical system () is arranged for providing the source light () as a collimated beam () onto the skin ().

Probe, system, and method for non-invasive measurement of blood analytes

The present disclosure concerns a spectrometer () and method for generating a two dimensional spectrum (S). The spectrometer () comprises a main grating () and cross dispersion element (). An imaging mirror () is arranged for reflecting and focussing dispersed radiation (R) from the main grating () towards an image plane (IP) for imaging the two dimensional spectrum (S) onto an image plane (IP) of the spectrometer (). A correction lens () is arranged for correcting optical aberrations in the imaging of the two dimensional spectrum (S) in the image plane (IP). The imaging mirror () and correction lens () have a coinciding axis of cylindrical symmetry (AS).

Spectrometer for generating a two dimensional spectrum

The present disclosure concerns a monolithic spectrometer for spectrally resolving light. The spectrometer comprises a body of solid material having optical surfaces arranged to guide the light along an optical path inside the body. A collimating surface and focusing surface are part of a single surface having a continuous optically functional shape. The surfaces of the body are arranged to have a third or fourth part of the optical path between a grating surface and an exit surface cross with a first part of the optical path between an entry surface and a collimating surface.

Monolithic spectrometer

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The Hague, Netherlands

Daniel Perez Calero