Astrazeneca Ab

Neomed Institute

Daniel Pagé

Christopher Walpole

Hua Yang

Ziping Liu

William Brown

Andrew Griffin

Niklas Plobeck

Paul Jones

Maxime Tremblay

Zhong-yong Wei

Zena Qadoumi

Sanjay Srivastava

Compounds of Formula (I) or pharmaceutically acceptable salts thereof; wherein R, R, R, and Rare as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain. 

Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Compounds of general formula: wherein R, Rand Rare as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders

Compounds of formula I or pharmaceutically acceptable salts thereof: wherein R, R, Rand Rare as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Therapeutic compounds

Compounds of Formula I, or pharmaceutically acceptable salts thereof: wherein R, R, R, R, R, and G are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Compounds, compositions containing them, preparation thereof and uses thereof I

Compounds of formula (I) or pharmaceutically acceptable salts thereof: wherein R, R, R, Rand Z are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain. 

Compounds of formula (I) or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, R4 and Z are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain. 

Compounds of formula (I) wherein R, R, Z, R, R, Ar, X and Y are as defined in the specification as well as salts and pharmaceutical compositions including the compounds were prepared. These compounds are useful in therapy, in particular in the management of pain. 

Compounds

Compounds of general formula (I) wherein R, Rand Rare as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain 

4(Phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain of gastrointestinal disorders

Compounds of formula (I) or pharmaceutically acceptable salts thereof: Formula (I) wherein R, R, RF, RFand Z are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain 

Growing community of inventors

St. Laurent, Canada

Daniel Pagé