Xyphos Biosciences Inc.

Daniel P Steiger

Kyle Landgraf

David W Martin, Jr

Steven R Williams

Dana Gebhart

Tarah Baron

This application relates generally to the production of polypeptides having specific antigen-binding properties of Fv domains, for example, insertable variable fragments of antibodies, and modified &#x3b1;1-&#x3b1;2 domains of NKG2D ligands.

Insertable variable fragments of antibodies and modified A1-A2 domains of NKG2D ligands

This application relates generally to the production of polypeptides having specific antigen-binding properties of Fv domains, for example, insertable variable fragments of antibodies, and modified &#x3b1;1-&#x3b1;2 domains of NKG2D ligands. This application further relates to modified &#x3b1;1-&#x3b1;2 domains of NKG2D ligands attached to polypeptides, in some embodiments antibodies or fragments of antibodies. This application further relates to antigen-binding peptides derived from light and heavy chain antibody variable domains, which contain two linker regions and a split variable domain.

Insertable variable fragments of antibodies and modified &#x3b1;1-&#x3b1;2 domains of NKG2D ligands

Insertable variable fragments of antibodies and modified &#x3b1;1-&#x3b1;2 domains of NKG2D ligands, and non-natural NKG2D ligands that bind non-natural NKG2D receptors

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San Francisco, CA, United States of America

Daniel P Steiger