University of Southern California

Daniel P Holschneider

Jean-Michel I Maarek

Eduardo H Rubinstein

Oscar U Scremin

Oscar V Scremin

Cesar Escobar Blanco

Frances Richmond

Alan J Eskovitz

A system for evaluating the cardiovascular system parameters using indicator dilution and non-invasive or minimally invasive detection and calibration methods are disclosed. Intravascular indicators are stimulated, and emissions patterns detected for computation of cardiac output, cardiac index, blood volume and other indicators of cardiovascular health.

System for repetitive measurements of cardiac output in freely moving individuals

A system and method of non-invasive or minimally invasive evaluating the cardiovascular system parameters to estimate the cardiac output and circulating blood volume of a patient undergoing hemodialysis. Intravascular indicators are stimulated, and emissions patterns detected for computation of cardiac output, cardiac index, blood volume and other indicators of cardiovascular health before and during hemodialysis.

Measurement of cardiac output and blood volume by non-invasive detection of indicator dilution for hemodialysis

A non-invasive system and method for determination of cardiac output and blood volume of a patient includes compensating for a change in the fluorescence of an indicator circulating in the bloodstream of a tissue or organ that is caused by a variation of the blood content at the site of the measurement.

Cardiac output monitor with compensation for tissue perfusion

Measurement of cardiac output and blood volume by non-invasive detection of indicator dilution

A system for evaluating the cardiovascular system parameters using indicator dilution and non-invasive or minimally invasive detection methods is disclosed. Intravascular indicators are stimulated, and emissions patterns detected for computation of cardiac output, cardiac index, blood volume and other indicators of cardiovascular health.

Method for dye injection for the transcutaneous measurement of cardiac output

A system for evaluating the cardiovascular system parameters using indicator dilution and non-invasive or minimally invasive detection methods is disclosed. Intravascular indicators are stimulated, and emission patterns detected for computation of cardiac output, cardiac index, blood volume and other indicators of cardiovascular health.

An implantable microbolus infusion pump is disclosed which includes an elastically deformable reservoir, an electrically activated microvalve, and a remotely activated control system. The control system includes a sensor that can be remotely activate, for example, magnetically or by infrared light. The pump can provide bolus infusion of pharmacologic agents. The pump is also capable of providing sequential release of a plurality of drugs.

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Los Angeles, CA, United States of America

Daniel P Holschneider