Cardiac Pacemakers, Inc.

Daniel O'Brien

Donald Lee Hopper

Paul F Emerson

Michael A Querimit

Jeffrey E Stahmann

Gary Thomas Seim

Stephen R Pitzl

Brian Ralph Larson

A cardiac rhythm management (CRM) device can extract ventilation information from thoracic impedance or other information, and adjust a delivery rate of the CRM therapy. A tidal volume of a patient is measured and used to adjust a ventilation rate response factor. The measured tidal volume can optionally be adjusted using a ventilation rate dependent adjustment factor. The ventilation rate response factor can also be adjusted using a maximum voluntary ventilation (MVV), an age predicted maximum heart rate, a resting heart rate, and a resting ventilation determined for the patient. In various examples, a global ventilation sensor rate response factor (for a population) can be programmed into the CRM device, and automatically tailored to be appropriate for a particular patient.

Ventilation sensor rate response normalization and calculation

A rate-adaptive pacemaker and a method for its operation in which the response factor for a minute ventilation sensor or other type of exertion level sensor is automatically set during a parameter adjustment mode that utilizes an activity level measurement to determine when the patient is at a target activity level with which is associated an appropriate target pacing rate. In a preferred embodiment, the target activity level corresponds to casual walking (e.g., 2 mph at a 4% grade) with a target pacing rate selected as appropriate for that level of activity in the individual patient.

Automatic programming of rate-adaptive therapy via activity monitoring

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Saint Paul, MN, United States of America

Daniel O'Brien