W. L. Gore & Associates, Inc.

Carmeda Ab

Daniel Nyström

Per Antoni

Krzysztof Pietrzak

Paul Christopher Begovac

Karin Leontein

Eva Koch

Christian Porsch-grahm

Lars Vincent

Helena Göransson

Anna Gällhagen

Malin Eriksson

Paul Begovac

According to the invention there is provided inter alia a process for the manufacture of a solid object having a surface comprising a layered coating of cationic and anionic polymer wherein the outer coating layer comprises an anticoagulant entity, comprising the steps of:

Processes for immobilising biological entities

There is described inter alia a device having a surface comprising a layered coating wherein the outer coating layer comprises a plurality of cationic hyperbranched polymer molecules characterized by having (i) a core moiety of molecular weight 14-1,000 Da (ii) a total molecular weight of 1,500 to 1,000,000 Da (iii) a ratio of total molecular weight to core moiety molecular weight of at least 80:1 and (iv) functional end groups, whereby one or more of said functional end groups have an anti-coagulant entity covalently attached thereto.

Immobilised biological entities

There is provided inter alia a substrate with a surface having a hydrophilic coating comprising a cross-linked copolymer of components A and B, and optional components C and D; wherein

Coating for substrate

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Upplands Väsby, Sweden

Daniel Nyström