Mcneil-ppc, Inc.

Daniel McTeigue

David W Wynn

Indukumar G Shah

Karen Swider

Thomas E Sox

Walter G Gowan, Jr

Richard D Fegley

Ravivaj S Pillai

Narenda Parikh

Taste masked particles and chewable tablets made therefrom are disclosed. The taste masked particles comprise a core containing an active ingredient and a polymeric coating covering said core, said coating comprising a mixture of a) an enteric polymer; and b) an insoluble film forming polymer, the surface of said particle being free of active ingredient. The chewable tablets provide immediate release of the active ingredient.

Teste masked pharmaceutical particles

The present invention provides a core of predominately microcrystalline cellulose, on which an active drug is layered onto the core via solution coating. The coated particles have a narrower particle size distribution than coated granules provided by other processes. An optional final coating of a pharmaceutically acceptable polymeric coating is provided to provide tastemaking or controlled release, and protection of the drug-layered particles.

Microcrystalline cellulose particles having active core

The present invention provides a quick dissolving, readily broken substrate suitable for the addition of pharmaceutical agents for oral administration. A method for making the substrate is also disclosed.

Stable foam composition

Preparation of pharmaceutically active particles

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North Wales, PA, United States of America

Daniel McTeigue