University of Washington

Bloodworks

Puget Sound Blood Center

Daniel M Ratner

Shaoyi Jiang

Norman David Brault, Jr

Jill Marie Johnsen

James T Kirk

José A López

Shieng Liu

Fong-Li Chou

Jae-Hyun Chung

Kyong-Hoon Lee

Dayong Gao

Jeffrey W Chamberlain

Kie Seok Oh

Gareth Fotouhi

Woonhong Yeo

Patrick S Stayton

Anthony Convertine

Selvi Srinivasan

Debobrato Das

Jose A Lopez

Photonic devices, systems, and methods for detecting an analyte in a biological solution (e.g., whole blood) are provided. Representative photonic devices are optical ring resonators having nanoscale features and micron-sized diameters. Due to the compact size of these devices, many resonators can be disposed on a single substrate and tested simultaneously as a sample is passed over the devices. Typical analytes include blood cells, antibodies, and pathogens, as well as compounds indicative of the presence of blood cells or pathogens (e.g., serology). In certain embodiments, blood type can be determined through photonic sensing using a combination of direct detection of blood cells and serology. By combining the detection signals of multiple devices, the type of blood can be determined.

Photonic pathogen detection

Photonic blood typing

Polymeric carriers for the delivery of therapeutic agents and methods for making and using the same. The polymeric carriers include copolymers, diblock copolymers, polymeric architectures that include the copolymers and diblock copolymers, and particles assemblies comprising the copolymers, diblock copolymers, and polymeric architectures that include the copolymers.

Stabilized polymeric carriers for therapeutic agent delivery

Methods and systems are provided for concentrating particles (e.g., bacteria, viruses, cells, and nucleic acids) suspended in a liquid. Electric-field-induced forces urge the particles towards a first electrode immersed in the liquid. When the particles are in close proximity to (e.g., in contact with) the first electrode, the electrode is withdrawn from the liquid and capillary forces formed between the withdrawing electrode and the surface of the liquid immobilize the particles on the electrode. Upon withdrawal of the electrode from the liquid, the portion of the electrode previously immersed in the liquid has particles immobilized on its surface.

Particle concentration system

Method and system for concentrating particles from a solution

Growing community of inventors

Seattle, WA, United States of America

Daniel M Ratner