Advanced Cardiovascular Systems, Inc.

Abbott Cardiovascular Systems, Inc.

Cardiac Pacemakers, Inc.

Spirox Corporation

Advanced Cardiovascular, Inc.

Daniel L Cox

Timothy A Limon

Paul M Consigny

William Earl Webler, Jr

Matthew J Fitz

Christopher Feezor

William James Harrison

Jessica G Chiu

Hongzhi Bai

Michael Schultz

Gustavo D Cipolla

John Francis Boylan

Gordon S Stewart

Benny Serna

Joseph A Ventura

Stephen D Pacetti

Darrin James Kent

David K Wrolstad

Anuja H Patel

Diem Uyen Ta

Christopher J Tarapata

Andreina P Gomez

Leonard Darius Barbod

Jessie Delgado

Kenneth Kay Armstrong

Thomas Ray Hatten

Caroline Wu

Brenna K Hearn

Wouter Erik Roorda

Brian D Soltis

Gregory M Hyde

Richard Roy Newhauser, Jr

Michael Stephan Mirizzi

Paul E Zarembo

Scott J Baron

Kent C B Stalker

Benjamyn Serna

E Tina Cheng

Kenny L Dang

Brett W Cryer

Gregory R Ley

Orlando M Padilla

Pamela A Kramer-Brown

Jeffrey T Ellis

Piyush Arora

Gene Michal

Richard T Allen

Joe Ventura, Ii

Gordon Steward

Mathew J Fitz

Josepher A Ventura

Stephen Dirk Pacetti

In another example, a bioresorbable implant for use in a nasal region includes one or more bioresorbable polymers, and a pharmaceutical composition coupled to the one or more bioresorbable polymers. A release rate of the pharmaceutical composition is related to a degradation rate of the one or more bioresorbable polymers.

Allergic rhinitis drug delivery implant

Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.

Methods and devices for eluting agents to a vessel

A catheter configured for delivering an agent to a patient's vessel wall is described. The catheter includes an inflatable balloon substantially covered by a expandable cage such that when the inflatable balloon is inflated the expandable cage substantially surrounds an outer surface of the inflated balloon. The inflatable balloon is configured to be deployed within a lumen against a lumen wall and separated from the lumen wall by the expandable cage in an expanded state, and is adapted to provide an agent delivery to a treatment site, and the expandable cage is further collapsible and is removable from said lumen.

Local delivery with a balloon covered by a cage

Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion.

Apparatus to prevent reperfusion injury

A stent for implantation in a body lumen for protecting from rupture a fibrous cap in order to treat vulnerable plaque. One embodiment of the stent achieves staged expansion through stronger and weaker circumferential regions, and includes optional anchors positioned at the circumferential transition between the stronger and weaker regions. During the first stage expansion, the weaker region expands moving the anchors laterally apart. The anchors straddle the fibrous cap and embed into the vessel wall. The second stage expansion of the stent exerts gentler stresses by the weaker region against the fibrous cap while the stronger region exerts greater stresses on the remainder of the vessel wall to open the vessel.

Stent with anchors to prevent vulnerable plaque rupture during deployment

An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for rupturing a fibrous cap to controllably release vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by links. The stent includes struts and links of varying strengths about the circumference of the stent. The weaker struts and links require less force to open and, hence, may apply more stress to rupture the fibrous cap while the stronger struts and links protect the healthy portions of the body lumen. In another embodiment, the stent may include stress concentrators positioned on outer surfaces of the links. The stress concentrators are aligned with the fibrous cap prior to stent expansion so that upon stent expansion, the stress concentrators induce stress to rupture the fibrous cap, thereby releasing the vulnerable plaque.

Intravascular stent for treating vulnerable plaque and method of use

A medical device that can be used for treating a defective heart valve. One aspect of the invention pertains to a longitudinally adjustable medical device that comprises a distal portion, a proximal portion, and a cord member. The distal portion comprises a distal anchoring member, a distal telescope, and a distal backbone. The proximal portion comprises a proximal anchoring member, a proximal telescope, and a proximal backbone. The distal backbone and the proximal backbone are configured to provide a structural support to the device while providing flexibility to the device. The cord member is disposed within the device and used to facilitate longitudinal adjustment for the device.

Telescoping apparatus for delivering and adjusting a medical device in a vessel

Growing community of inventors

Palo Alto, CA, United States of America

Daniel L Cox