Uwm Research Foundation, Inc.

Medical University of Vienna

National Taiwan University

University Of Belgrade—faculty Of Pharmacy

Daniel Knutson

James M Cook

Marko Mihovilovic

Miroslav M Savic

Lih-Chu Chiou

Pi-Chuan Fan

Werner Sieghart

Laurin Wimmer

Matheus Meirelles

Margot Ernst

Ranjit Verma

Zdravko Varagic

David Chan Bodin Siebert

Christopher Witzigmann

Provided herein are novel pyrazoloquinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis; depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus.

Ligands selective to alpha 6 subunit-containing GABAA receptors and their methods of use

Provided herein are novel pyrazolo-quinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis; depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus.

Growing community of inventors

Elkhorn, WI, United States of America

Daniel Knutson