Beijing University of Technology

Puretech Lyt, Inc.

Other

Seaport Therapeutics, Inc.

Daniel Kenneth Bonner

Sifei Han

Luojuan Hu

Jamie Simpson

Natalie Trevaskis

Rishab R Shyam

Ketki Karanam

Tim Quach

Christopher John Hamilton Porter

Christopher John Porter

James Tendai Mutamba

Joseph Bonner

Joseph R Bonner

Larry Dugan

The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a provided lipid prodrug or a pharmaceutical composition thereof.

Lymphatic system-directing lipid prodrugs

The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, as well as methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.

Lipid prodrugs of neurosteroids

The present invention provides lymphatic system-directing lipid prodrugs, pharmaceutical compositions thereof, methods of producing such prodrugs and compositions, and methods of improving the bioavailability or other properties of a therapeutic agent that comprises part of the lipid prodrug. The present invention also provides methods of treating a disease, disorder, or condition such as those disclosed herein, comprising administering to a patient in need thereof a disclosed lipid prodrug or a pharmaceutical composition thereof.

Lipid prodrugs of mycophenolic acid and uses thereof

Lipid prodrugs of rapamycin and its analogs and uses thereof

Spinner blade

A cranking device for use with a winch having a crankable shaft, the cranking device comprising an engagement member selectively engageable with an end of the crankable shaft in a loose fitting relationship such that the engagement member may be rotated relative to the shaft end, a handle fixed to the engagement member for cranking same, a locking mechanism provided with the engagement member for locking the engagement member onto the end of the crankable shaft in the loose fitting relationship such that the shaft may be cranked together with the engagement member under relatively low torque. Additionally, the engagement member is preferably formed as a socket having a plurality of spacer members provided on an inner surface thereof for engaging the shaft end when the socket is fitted thereover such that a gap is defined between an outer periphery of the shaft and an inner periphery of the socket.

Low torque cranking device and methods of constructing and utilizing same

Growing community of inventors

Sharon, MA, United States of America

Daniel Kenneth Bonner