Princeton University

Daniel K Walter

William Happer

Gordon D Cates, Jr

Bastiaan Driehuys

Brian Saam

Eli Miron

Hunter Middleton

The present invention relates to a method and system for using end resonances of highly spin-polarized alkali metal vapors for an atomic clock, magnetometer or other system. A left end resonance involves a transition from the quantum state of minimum spin angular momentum along the direction of the magnetic field. A right end resonance involves a transition from the quantum state of maximum spin angular momentum along the direction of the magnetic field. For each quantum state of extreme spin there are two end resonances, a microwave resonance and a Zeeman resonance. The microwave resonance is especially useful for atomic clocks, but it can also be used in magnetometers. The low frequency Zeeman resonance is useful for magnetometers.

Method and system for operating an atomic clock with reduced spin-exchange broadening of atomic clock resonances

A method and apparatus for accumulation of hyperpolarized .sup.129 Xe is disclosed. The method and apparatus of the invention enable the continuous or episodic accumulation of flowing hyperpolarized .sup.129 Xe in frozen form. The method also permits the accumulation of hyperpolarized .sup.129 Xe to the substantial exclusion of other gases, thereby enabling the purification of hyperpolarized .sup.129 Xe. The invention further includes .sup.129 Xe accumulation means which is integrated with .sup.129 Xe hyperpolarization means in a continuous or pulsed flow arrangement. The method and apparatus enable large scale production, storage, and usage of hyperpolarized .sup.129 Xe for numerous purposes, including imaging of human and animal subjects through magnetic resonance imaging (MRI) techniques.

Cryogenic accumulator for spin-polarized xenon-129

A method and apparatus for hyperpolarization of flowing noble gases is disclosed, including means for hyperpolarization of noble gases in a continuous flow arrangement. Noble gases such as xenon-129 and helium-3 can be hyperpolarized using the disclosed method and apparatus. Preferably, the noble gas is hyperpolarized via spin exchange between atoms of the noble gas and an alkali metal such as rubidium. Also, a method and apparatus for accumulation and/or storage of hyperpolarized noble gases in a continuous flow arrangement is provided. The method and apparatus enable large scale production, storage, and usage of hyperpolarized noble gases for numerous purposes, including imaging of human and animal subjects through magnetic resonance imaging (MRI) techniques.

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Falls Church, VA, United States of America

Daniel K Walter