Boehringer Ingelheim Vetmedica Gmbh

Boehringer Ingelheim Animal Health USA Inc.

Daniel John Murfin

Eric Martin Vaughn

Michael B Roof

Marc Allan Eichmeyer

Merrill Lynn Schaeffer

Kun Yang

Jeremy Richard Rush

The invention provides methods and mass-labeled peptides for use in said methods for quantifying the presence of a one or more viral proteins in a sample of a preparation containing agents which bind to said viral protein, using mass-spectroscopic analyses of the sample and standards containing known amounts of labeled and unlabeled signature peptides, in particular wherein said viral proteins are antigens in a vaccine for porcine circovirus.

Quantification of vaccine compositions

The invention provides methods and mass-labeled peptides for use in said methods for quantifying the presence of a one or more viral proteins in a sample of a preparation containing agents which bind to said viral protein, using mass-spectroscopic analyzes of the sample and standards containing known amounts of labeled and unlabeled signature peptides, in particular wherein said viral proteins are antigens in a vaccine for porcine circovirus.

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St. Joseph, MO, United States of America

Daniel John Murfin