Duke University

Daniel Joh

Ashutosh Chilkoti

Angus Hucknall

Michael S Hershfield

Benjamin B Yellen

Aaron Franklin

Joseph Batton Andrews

Yizhi Qi

Nancy J Ganson

Roozbeh Abedini-Nassab

Disclosed herein are compositions and methods for reducing the antigenicity of molecules. The antigenicity of a molecule may be reduced or eliminated by conjugating at least one branched polymer to the molecule to form a molecule-polymer conjugate. The branched polymer may include a backbone and a plurality of side chains, each side chain covalently attached to the backbone.

Surfaces having reduced non-specific binding and antigenicity

Disclosed are sensors that include a carbon nanotube channel and a non-fouling polymer layer, where the non-fouling polymer layer and the carbon nanotube channel do not directly contact each other and are separated by a dielectric layer. The disclosed sensors may be used, e.g., as biosensors for the accurate and sensitive detection of analytes within a sample. Also disclosed are methods of making and using the sensors.

Nonfouling biosensors

Growing community of inventors

Durham, NC, United States of America

Daniel Joh