Coapt Systems, Inc.

Absolutions Med, Inc.

Leland Stanford Junior University

Trigemina, Inc.

Healthpartners Research Foundation

Shalon Ventures, Inc.

Airxpanders, Inc.

Nocicepta LLC

Svip5 LLC

Healthpartners Research & Education

Airx Bioscience, LLC

Daniel Jacobs

David C Yeomans

Martin S Angst

Tadmor Shalon

Gregory Lamps

William Howard Frey, Ii

Christopher Scott Jones

Robert J Elson

Brad Richardson

David S Mintz

Craig A Purdy

F Mark Payne

Ryan S Han

Matthew Luis Rivera

Samuel P Sawan

Lawrence Robert Toll

John H Morriss

Sean S Cahill

Kourosh Kojouri

Jude V Paganelli

Dirk Thye

Leigh Boros

Frederick Mark Payne

Mark F Payne

Robert James Elson

Scott Wetenkamp

A combined magnetic and bioabsorbable device for ventral hernia closure and/or tension distribution for maintenance of tissue apposition for healing, while avoiding a long-term footprint of foreign material and precluding materials spanning the interior layer of the abdominal closure where risk to visceral structures exists.

Abdominal closure method and device variations for closing ventral hernias and reducing recurrence

Abdominal approximation devices and methods are described where one variation of the tissue securement assembly may generally include a fixation member having a length, a thickness control securement member which is adjustably securable along the length, and a frame which is adjustably securable to the thickness control securement member. The frame may have a relaxed configuration and a biasing configuration which imparts a biasing force against the thickness control securement member when in the biasing configuration such that the biasing force is applied at a distance from tissue to be approximated via the fixation member.

Abdominal approximation device and method

Abdominal closure reinforcement methods and tissue anchoring devices for reducing the rate of abdominal wall closure dehiscence are described. The tissue anchors avoid a permanent footprint of foreign material and precluding materials spanning the interior layer of the abdominal closure where risk to visceral structures exists.

Abdominal closure method and device variations

An abdominal closure method and device is disclosed where the device generally includes a first tissue securement member configured for securement to a first tissue region and a second tissue securement member configured for securement to a second tissue region. The first and second tissue securement members are coupled to the connecting member and the connecting member is positionable at a distance from the first and second tissue regions. Additionally, one or more biasing elements may be connected to the first and second tissue securement members to approximate the first and second tissue regions towards one another via respective securement members.

Abdominal closure method and device for ventral hernia

Tissue expanders and their methods of use.

Tissue expanders and methods of use

Particles of an organic acid salt of an amino acid amide or ester local anesthetic are employed as agents for the improved alleviation of pain. Particularly, the particles find use with surgically created wounds, where the particles may be administered directly into the bed of the wound or topically for transdermal transport.

Slow release of organic salts of local anesthetics for pain relief

The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N/OFQ). Intranasal administration of certain analgesic peptides such as N/OFQ results in global analgesic effects.

Methods for treatment of pain

The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.

Methods for treatment of headaches by administration of oxytocin

Growing community of inventors

Mountain View, CA, United States of America

Daniel Jacobs