Gyroscope Therapeutics Limited

Orbit Biomedical Limited

Becton Dickinson and Company Limited

Ethicon, Gmbh

Tornier, Inc.

Genentech, Inc.

Cilag International Gmbh

Ethicon Endo-surgery, Inc.

Preciflex Sa

Precifiex Sa

Daniel J Yasevac

Michel Bruehwiler

Saeed Sokhanvar

Daniel W Price

Brendan J Oberkircher

Leah R Soffer

Cole Constantineau

Michael F Keane

Isaac John Khan

Nathan Daniel Grubbs

Benjamin L Ko

Christopher D Riemann

Judy Lin Walish

Jeffrey Thomas Chagnon

Mary Teresa Carter

Kevin D Felder

Melissa Rosen

Kevin DelSignore

Lucien Vouillamoz

Daniel Morgan

Justin C Anderson

Douglas B Snell

John A Hibner

Gregory W Johnson

Sean P Conlon

Urban Schnell

William D Dannaher

Ryan Everett Schoonmaker

Russell S Cole

David James Cagle

Sudarsan Srinivasan

Stefan Troller

David Alexander Monroe

Eric Bene

Tyson Montidoro

Veaceslav Arabagi

Mohammadreza Ramezanifard

Alain Saurer

Urban G Schnell

Mohammadreza Ramerzanifard

Daniel E Morgan

Michel G Bruehwiler

Chris Campbell

Jean Christophe Roulet

Kevin Delsignore

Veaceslav G Arabagi

Jean-Christophe Roulet

Mary T Carter

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

Method and apparatus for suprachoroidal administration of therapeutic agent

Method and apparatus for subretinal administration of therapeutic agent

Various exemplary systems, devices, and methods for robotic bi-polar instruments are provided. In general, a surgical tool can include an elongate shaft, an end effector, a wrist that couples the end effector to the shaft at a distal end of the shaft, and a tool housing coupled to a proximal end of the shaft that is configured to control the operation various features associated with the end effector and to operatively couple to a robotic surgical system.

Robotic bi-polar instruments

An attachable needle assembly () used on a medication delivery pen (), the needle assembly () comprising a spike () configured to pierce a vial, reservoir or cartridge septum of the pen (), a needle guide () configured to mate with the pen (), the needle guide () enclosing a septum () of the needle assembly () defining a septum chamber (), the septum chamber () being in fluid communication with the spike (), a plurality of needles () disposed in the septum () of the needle assembly (), a sterility barrier () enclosing each of the plurality of needles (), each of a plurality of sterility barriers () having a peel tab (), each of a plurality of peel tabs () being wrapped around the needle guide (), wherein when one of the plurality of needles () is drawn from the needle guide () from a first position to a second position, the needle () fluidly communicates with the septum chamber (), and the sterility barrier () and the peel tab () of the needle () are removed.

Pen needle magazine

Various exemplary systems, devices, and methods for articulating electrosurgical tools are provided. In general, a surgical tool can be configured to articulate in two planes by selectively pivoting at first and second joints of the surgical tool. The surgical tool can include a plurality of cables configured to facilitate the articulation. Each of the cables can be configured to flex or bend at the first and second joints and can be configured to be selectively actuated to cause the pivoting at the first and second joints. The surgical tool can be configured to releasably couple to a robotic surgical system configured to control a variety of movements and actions associated with the surgical tool, such as the pivoting at the first and second joints.

Articulating electrosurgical tools

Some embodiments of the present invention include a suture anchor with both knotless and knotted suture attachment capabilities, as well as methods for loading the suture in knotless and knotted configurations. Some embodiments of the present invention include a suture anchor with an inner implant body with a spreader that slides in relation to an outer expandable collar, such that pushing the expandable collar distally with an inserter causes the spreader to expand the collar against the surrounding bone to secure the suture anchor in place. Such embodiments may also include a detachment or breakaway feature between the inserter and the suture anchor to permit separation after anchor deployment. Some embodiments of the present invention include methods for deploying such suture anchors and expanding the expandable collars and/or detaching the inserter tools. Embodiments of the present invention may be used in various orthopedic applications such as, for example, shoulder repair.

Bone implant with convertible suture attachment

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, an actuation assembly, and a detection/visualization system. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis. The cannula may be inserted through a sclerotomy incision and advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer. The detection/visualization system is operable to detect or visualize penetration of the choroid of a patient's eye and provide feedback to the operator and/or automatic control of the apparatus based on penetration of the choroid.

Method and apparatus for sensing position between layers of an eye

An apparatus for delivering therapeutic agent to an eye includes a body, a cannula, a hollow needle, and an actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy incision to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

An apparatus for delivering therapeutic agent to an eye comprises a body, a cannula, a hollow needle, and an automated actuation assembly. The cannula extends distally from the body and is sized and configured to be insertable between a choroid and a sclera of a patient's eye. The actuation assembly is operable to actuate the needle relative to the cannula to thereby drive a distal portion of the needle along an exit axis that is obliquely oriented relative to the longitudinal axis of the cannula. The cannula may be inserted through a sclerotomy to position a distal end of the cannula at a posterior region of the eye, between the choroid and sclera. The needle may be advanced through the choroid to deliver the therapeutic agent adjacent to the potential space between the neurosensory retina and the retinal pigment epithelium layer, adjacent to the area of geographic atrophy.

Motorized suprachoroidal injection of therapeutic agent

An active agent or drug injecting device () includes a main housing () containing a trigger mechanism () which can be manually activated via release bar () or remotely triggered via wireless receiver () activating motor (), and a second housing () containing an injection- and needle-assembly (). The needle () encloses a dry carrier () having an active agent () disposed thereon. The trigger mechanism triggers the injection assembly to propel the needle into the skin (via spring ()), to inject the active agent into a living organism (either by letting the active agent diffuse out of the needle or by actively flushing it out), and to subsequently retract the needle back into the housing () (via spring ()).

Skin-attachable miniature drug injection device with remote activation capability and dry drug carrier within injection needle

An infusion set adapted to be secured to a skin surface includes a fixed base member connectable to the skin surface and a movable member. A needle or cannula is connected to the movable member and movable relative to the fixed base member. The movable member is movable from a first position in which the needle or cannula is not exposed externally of the fixed base member to a second position in which the needle or cannula is exposed externally of the fixed base member. A release member retains the movable member in the first position. Removal of the release member allows movement of the movable slide member to the second position.

Automatic angled infusion set assembly

A fluid dispensing device is provided for dispensing a measured amount of fluid into a living organism. The device has a needle having a first end and a second end. The needle is adapted for interfacing, on the first end, with a septum of a flexible hollow membrane, and at a second end thereof, for subcutaneously inserting into a living organism. The needle is guided by a guide to permit an injection into the living organism at a substantially non-orthogonal angle with respect to a surface of the living organism. The first and second ends of the needle pierce their respective piercing surface while translating together in a common direction. In other embodiments, the dispensing device includes a main housing, a flexible fluid reservoir, an injection assembly and a trigger mechanism. The main housing houses the operative components of the device.

Fluid dispenser

Growing community of inventors

Somerville, MA, United States of America

Daniel J Yasevac