Cook Medical Technologies LLC

Cook Incorporated

Cook Critical Care Incorporated

Daniel J Sirota

Ram H Paul, Jr

Darin Gene Schaeffer

Andrew K Hoffa

Frank J Fischer, Jr

Michael C Hoffa

James B Hunt

Bruce Gingles

Paul D Amarant

Jason C Urbanski

Anthony C Venbrux

Ram H Paul

Frank J Fischer

A hemostatic device includes a dissolvable coating and a hemostatic substance enclosed within the coating. The device can have, for example, a generally spherical shape. The hemostatic substance can be particles that take any shape, such as spherical, flat sheets, cubes, or other regular or irregular shapes of any size or volume that can be used on or within a body.

Hemostatic substance with a coating

A closure device includes a bioremodelable patch and a joining element linking one or more bioremodelable patches to tissue portions adjacent to a bodily opening. The closure device may include a pair of bioremodelable patches linked by sutures and compressively joined to overlapping tissue portions adjacent to the opening. The closure device may be further contained within an assembly additionally including a catheter having a hollow sheath and a pusher. The pusher may be used to dislodge one or more bioremodelable patches from the catheter to facilitate stable closure of a bodily opening, such as a septal opening in a PFO.

Closure device with biomaterial patches

A wire guide and a method for its percutaneous guidance within a body vessel are provided. The wire guide includes an outer component for insertion into the body vessel and a core wire disposed in the outer component and movable between first and second positions. The core wire includes an engaging portion that extends from the outer component to engage the body vessel when the core wire is in the second position.

Wire guide with engaging portion

A medical device is adapted for at least partial implantation into a body and includes first and second sections along the length of the device. A first therapeutic agent is associated with the first section and a second therapeutic agent is associated with the second section. The first therapeutic agent can be one or more antiproliferative, such as paclitaxel, a paclitaxel derivative, or a paclitaxel pro-drug, anti-coagulant, antithrombotic, thrombolytic, fibrinolytic, or combination thereof. The second therapeutic agent can be one or more antimicrobials, such as one or more antibiotics. Each of the first and second therapeutic agents can either be posited on one or more surfaces of the respective section, or impregnated within the section. The device can include a separator to space the first and second sections. A method of making a medical device and a method of establishing access to a vessel within a body are also provided.

Medical device with therapeutic agents

An apparatus and method for inserting an article into a body opening. A radially expandable introducer sheath is delivered in a non-expanded condition into a body opening. A release mechanism releases the introducer sheath from the non-expanded condition into a condition that permits radial expansion of the introducer sheath upon introduction of a medical device through the sheath into the body opening. An optional handle having a circumferential opening may be provided for withdrawing the sheath from the body opening, while leaving the medical device in place.

Introducer sheath

The present invention is directed toward a surgical drape having a base sheet and an absorbent sheet with at least one opening. A transparent or clear sheet is attached to the edges of the opening and has at least one fenestration for performing surgery when the drape is covering a patient.

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Bloomington, IN, United States of America

Daniel J Sirota