Massachusetts Eye and Ear Infirmary

Harvard College

Daniel J Lee

Aaron K Remenschneider

Jennifer Ann Lewis

Michael J McKenna

David B Kolesky

Mark Andrew Skylar-Scott

John Rosowski

Elliott Kozin

Alexander D Valentine

Nicole Black

Albert Edge

Heidi Nakajima

Song Cheng

Elliot Kozin

Xiankai Meng

Michael J Mckenna

The invention relates to multimodal, e.g., bimodal, hybrid cochlear implants that provide both optical (optogenetic) as well as electrical stimulation to enhance sensitivity.

Bimodal hybrid cochlear implants

This disclosure features artificial tympanic membrane graft devices and two-component bilayer graft devices that include a scaffold having a plurality of ribs made of a first material and a plurality of spaces between the ribs filled or made with the first material, a different, second material, a combination of the first and a second materials, or a combination of a second material and one or more other different materials. The bilayer graft devices have two components or layers. One component, e.g., the underlay graft device, can include a projection, and the second component, e.g., the overlay graft device, can include an opening that corresponds to the projection (or vice versa) so that the opening and the projection can secure the two layers together in a 'lock and key' manner. This disclosure also features methods of making, using, and implanting the three-dimensional artificial tympanic membrane and bilayer graft devices.

Artificial tympanic membrane devices and uses

This disclosure features elongated prosthetic devices that can be used to repair, e.g., resurface or occlude, a defect of a semicircular canal, e.g., a superior semicircular canal dehiscence, as well as methods of making and using these devices. For example, the devices can be made using three-dimensional (3D) printing.

Prosthetic devices for semicircular canal defects

Growing community of inventors

Brookline, MA, United States of America

Daniel J Lee