Other

Affinergy Inc.

Daniel J Kenan

Mark W Grinstaff

Paul Theodore Hamilton

Jack D Keene

Ray Edward Benson

Robin Hyde-DeRuyscher

Dale J Christensen

Donald E Tsai

Wayne Fl Beyer

A method of generating a nucleic acid species which are immunologically cross-reactive with non-nucleic acid immunogens is disclosed. The method comprises combining an antigen binding protein which binds said immunogen with a degenerate pool of nucleic acid species, and then recovering a nucleic acid species bound by said antigen binding protein from said degenerate pool. Also disclosed are the nucleic acid species so made, along with the use thereof for tagging molecules for immunological detection, for detecting antibodies to predetermined non-nucleic acid immunogens, for blocking complex formation between an antigen binding protein and a non-nucleic acid immunogen, and for inducing an immune response to the immunogen in a human or animal subject. Preferred immunogens are peptides and preferred antigen binding proteins are antibodies.

Method for deriving epitopes

Growing community of inventors

Durham, NC, United States of America

Daniel J Kenan