Boston Scientific Scimed, Inc.

Boston Scientific Corporation

Daniel J Gregorich

Michael P Meyer

Tracee E Eidenschink

Soo-Young Yoon

Matt Heidner

Timothy Samuel Girton

Yousef F Alkhatib

Adam Jennings

Karl Alan Jagger

John B Blix

Jan Weber

Jonathan Swift Stinson

Derek C Sutermeister

Brent C Gerberding

Richard Charles Gunderson

Brian J Brown

Jason Todd Lenz

Gordon Kocur

Derek Wise

James M Anderson

Hans F Valencia

Liliana Atanasoska

Andrzej M Malewicz

Oscar R Carrillo, Jr

Paul F Chouinard

Timothy J Mickley

Tracee E J Eidenschink

John Allen Hingston

Torsten Scheuermann

Roger W McGowan

Thomas E Broome

Richard J Olson

Matthew J Miller

Adam David Grovender

Amnon Yadin

Shawn Sorenson

Liza J Davis

Richard C Tooley

Dominick Godin

Kimberly Robertson

Matthew Frost

Selina Merkling

Johnathan J Braun

Adam Huot

David L Friesen

Michael L Davis

Timothy Lawrence Rubesch

Angela Kornkven Volk

David Raab

Michael J Tierney

Eric Michael Petersen

Gary John Pederson, Jr

Samuel Robaina

James Lee Shippy, Iii

Todd Rowe

Katherine Stryker Brodeen Routh

David D Groneberg

Kevin Martin

Jens Hegg

Corey Tillman

Kevin Grotheim

Ryan S Bennett

Aaron Foss

Laura Finn Miller

Jordan Pollack

Jonathan Patrick Wittrock

Adam Jennigs

Selina M Merkling

Ben Gundale

Chuck Rundquist

Matthew Nelson Frost

Kimberly Anne Robertson

Gordon J Kocur

Tracee EJ Eidenschink

James Lee Shippy Iii

Michael Meyer

Kevin P Grotheim

James E Mcgovern

Hans Valencia

The present disclosure relates to the field of endoscopy. Specifically, the present disclosure relates to systems and methods for en bloc resection of malignant and pre-malignant lesions and/or tumors within the gastrointestinal (GI) tract. More specifically, the present disclosure relates to systems and methods for delivering an expandable scaffold between tissue layers (e.g., between the muscularis and submucosa layers) to elevate and stabilize the lesion or tumor for fast and efficient resection.

Expandable scaffolds for submucosal tissue separation

Loading tools for use with medical devices are disclosed. An example loading tool may be suitable for use with a drug-coated expandable medical device. The loading tool may include a tubular sleeve having a distal end region, a proximal end region, and a lumen extending therethrough. The distal end region may include a reduced distal tip designed to interact with a hemostasis valve having a resilient seal member.

Loading tools for use with medical devices

Medical device systems and methods for making and using medical device systems are disclosed. An example medical device system may include a guidewire. A pressure sensor assembly may be disposed within the guidewire. The pressure sensor assembly may include a pressure sensor and a first optical fiber coupled to the pressure sensor. The first optical fiber may have a first outer diameter. A cable may be coupled to the guidewire. The cable may include a second optical fiber. The second optical fiber may have a second outer diameter greater than the first outer diameter.

Pressure-sensing medical devices and medical device systems

Medical devices and methods for making and using medical devices are disclosed. An example method may include a method for calculating fractional flow reserve including providing a pressure sensing guidewire, advancing the pressure sensing guidewire through a blood vessel to a first position distal of an intravascular occlusion, determining a distal pressure within the body lumen with the pressure sensing guidewire, proximally shifting the pressure sensing guidewire to a second position proximal of the occlusion, determining a proximal pressure within the body lumen with the pressure sensing guidewire, measuring an aortic pressure, and calculating a pressure drift. The pressure drift may be the difference between the aortic pressure and the proximal pressure. The method may also include calculating a drift-compensated fractional flow reserve. The drift-compensated fraction flow reserve may correspond to (the distal pressure+the pressure drift) divided by the aortic pressure.

Pressure sensing guidewire and methods for calculating fractional flow reserve

A device for treating tissue may include a tissue expander configured to be inserted into a body lumen and stretch tissue surrounding the body lumen, and a tool configured to be coupled to the tissue expander and move along a path defined by the tissue expander.

Resection tools and related methods of use

Medical devices such as catheters can include structure or provision that permit a physician or other health care professional to adjust the stiffness of at least a portion of the medical device. In some instances, the medical device may be adjusted prior to inserting the medical device into a patient. In some cases, the medical device may be adjusted while in use within the patient.

Adjustable stiffness catheter

Medical devices and methods for making and using medical devices are disclosed. An example medical device includes a pressure sensing guidewire. The pressure sensing guidewire may include a tubular member having a proximal portion and a distal portion. The distal portion may have a plurality of slots formed therein. The distal portion may have a first wall thickness along a first region and a second wall thickness different from the first wall thickness along a second region. A pressure sensor may be disposed within the distal portion of the tubular member.

Pressure sensing guidewire

A stent comprises a plurality of circumferential bands. Circumferential bands which are adjacent one another are connected one to the other. The circumferential bands include peaks and troughs interconnected by bent struts. The bands may overlap or may be connected by connectors.

Stent

Balloon catheters and stent delivery systems including bifurcated stent delivery systems are disclosed. An example bifurcated stent delivery system may include an elongate shaft including a proximal section, a midshaft section, and a distal section. The proximal section may include a tubular member having a plurality of slots formed therein. The slots may be arranged in one or more sections having differing slot densities. The midshaft section may include a guidewire port in fluid communication with a guidewire lumen formed in the shaft. A main branch balloon may be coupled to the shaft. A side branch balloon may be disposed adjacent to the main branch balloon. A stent may be disposed on the main branch balloon and on the side branch balloon.

Balloon catheter

A stent comprises a generally cylindrical band having a pattern of alternating first and second struts, the first struts being wider than the second struts, the first and second struts being of substantially the same length.

Flexible stent with improved axial strength

A medical implant includes a metallic base, a tie layer, and at least a first layer overlying an outer surface of the tie layer. The tie layer is bonded to at least a portion of a surface of the metallic base. The tie layer includes magnesium or a magnesium-based alloy. The tie layer can have an outer surface comprising dendritic grains. The tie layer can have a rough outer surface defined by pores, projecting grain structures, and/or projecting particles. A method of producing a tie layer on a medical device includes applying magnesium or a magnesium-based alloy to the medical device and cooling the magnesium or the magnesium-based alloy to produce a rough outer surface.

Medical implant including a magnesium-based tie layer

Described herein are implantable medical devices for delivering a therapeutic agent to the body tissue of a patient, and methods for making such medical devices. In particular, the implantable medical devices, such as intravascular stents, have a coating which includes at least one coating composition and has an exposed abluminal surface and an exposed luminal surface or exposed side surface.

Coating for medical device having increased surface area

Among other things, a bio-erodible implantable endoprosthesis comprises a member that includes (a) a core having a surface, and (b) a bio-erodible metal on a least a portion of the surface of the core, wherein the bio-erodible metal erodes more slowly than the core and includes openings through which physiological fluids can access the core upon implantation.

Endoprosthesis

Growing community of inventors

St. Louis Park, MN, United States of America

Daniel J Gregorich